Ananthan S - Search Results

1

SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.

Zhu J, Quizon PM, Wang Y, Adeniran CA, Strauss MJ, Jiménez-Torres AC, Patel P, Cirino TJ, Eans SO, Hammond HR, Deliscar LS, O'Hara P, Saini SK, Ofori E, Vekariya RH, Zhang S, Moukha-Chafiq O, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhan CG, McLaughlin JP. Zhu J, et al. Among authors: ananthan s. Neuropharmacology. 2022 Dec 1;220:109239. doi: 10.1016/j.neuropharm.2022.109239. Epub 2022 Sep 17. Neuropharmacology. 2022. PMID: 36126727

2

Identification of a novel partial inhibitor of dopamine transporter among 4-substituted 2-phenylquinazolines.

Ananthan S, Saini SK, Khare R, Clayton SD, Dersch CM, Rothman RB. Ananthan S, et al. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2225-8. doi: 10.1016/s0960-894x(02)00348-7. Bioorg Med Chem Lett. 2002. PMID: 12127543

3

Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.

Ananthan S, Kezar HS 3rd, Saini SK, Khare NK, Davis P, Dersch CM, Porreca F, Rothman RB. Ananthan S, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):529-32. doi: 10.1016/s0960-894x(02)00934-4. Bioorg Med Chem Lett. 2003. PMID: 12565965

4

Novel ligands for the opioid receptors: synthesis and structure-activity relationships among 5'-aryl and 5'-heteroaryl 17-cyclopropylmethyl-4,5 alpha-epoxypyrido[2',3':6,7]morphinans.

Ananthan S, Khare NK, Saini SK, Davis P, Dersch CM, Porreca F, Rothman RB. Ananthan S, et al. Bioorg Med Chem. 2003 Sep 1;11(18):4143-54. doi: 10.1016/s0968-0896(03)00432-2. Bioorg Med Chem. 2003. PMID: 12927876

5

Recombinant human immunodeficiency virus-1 transactivator of transcription1-86 allosterically modulates dopamine transporter activity.

Zhu J, Ananthan S, Mactutus CF, Booze RM. Zhu J, et al. Among authors: ananthan s. Synapse. 2011 Nov;65(11):1251-4. doi: 10.1002/syn.20949. Epub 2011 May 17. Synapse. 2011. PMID: 21538554 Free PMC article. No abstract available.

6

14-Alkoxy- and 14-acyloxypyridomorphinans: μ agonist/δ antagonist opioid analgesics with diminished tolerance and dependence side effects.

Ananthan S, Saini SK, Dersch CM, Xu H, McGlinchey N, Giuvelis D, Bilsky EJ, Rothman RB. Ananthan S, et al. J Med Chem. 2012 Oct 11;55(19):8350-63. doi: 10.1021/jm300686p. Epub 2012 Sep 27. J Med Chem. 2012. PMID: 23016952 Free PMC article.

7

Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.

Ananthan S, Saini SK, Zhou G, Hobrath JV, Padmalayam I, Zhai L, Bostwick JR, Antonio T, Reith ME, McDowell S, Cho E, McAleer L, Taylor M, Luedtke RR. Ananthan S, et al. J Med Chem. 2014 Aug 28;57(16):7042-60. doi: 10.1021/jm500801r. Epub 2014 Aug 15. J Med Chem. 2014. PMID: 25126833 Free PMC article.

8

Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency.

Rothman RB, Ananthan S, Partilla JS, Saini SK, Moukha-Chafiq O, Pathak V, Baumann MH. Rothman RB, et al. Among authors: ananthan s. J Pharmacol Exp Ther. 2015 Jun;353(3):529-38. doi: 10.1124/jpet.114.222299. Epub 2015 Mar 18. J Pharmacol Exp Ther. 2015. PMID: 25788711 Free PMC article.

9

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells.

Li Y, Lu W, Saini SK, Moukha-Chafiq O, Pathak V, Ananthan S. Li Y, et al. Among authors: ananthan s. Oncotarget. 2016 Mar 8;7(10):11263-70. doi: 10.18632/oncotarget.7019. Oncotarget. 2016. PMID: 26820295 Free PMC article.

10

Discovery of a novel inhibitor of kinesin-like protein KIFC1.

Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y. Zhang W, et al. Among authors: ananthan s. Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4. Biochem J. 2016. PMID: 26846349 Free PMC article.

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