Saxena S - Search Results

1

PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.

Pilotto F, Schmitz A, Maharjan N, Diab R, Odriozola A, Tripathi P, Yamoah A, Scheidegger O, Oestmann A, Dennys CN, Sinha Ray S, Rodrigo R, Kolb S, Aronica E, Di Santo S, Widmer HR, Charlet-Berguerand N, Selvaraj BT, Chandran S, Meyer K, Zuber B, Goswami A, Weis J, Saxena S. Pilotto F, et al. Among authors: saxena s. Acta Neuropathol. 2022 Nov;144(5):939-966. doi: 10.1007/s00401-022-02494-5. Epub 2022 Sep 19. Acta Neuropathol. 2022. PMID: 36121477 Free PMC article.

2

Neurotrophins and neurodegenerative diseases: receptors stuck in traffic?

Kruttgen A, Saxena S, Evangelopoulos ME, Weis J. Kruttgen A, et al. Among authors: saxena s. J Neuropathol Exp Neurol. 2003 Apr;62(4):340-50. doi: 10.1093/jnen/62.4.340. J Neuropathol Exp Neurol. 2003. PMID: 12722826 Review.

3

Trophic factors in neurodegenerative disorders.

Weis J, Saxena S, Evangelopoulos ME, Kruttgen A. Weis J, et al. Among authors: saxena s. IUBMB Life. 2003 Jun;55(6):353-7. doi: 10.1080/1521654031000153021. IUBMB Life. 2003. PMID: 12938738 Free article. Review.

4

Differences in the surface binding and endocytosis of neurotrophins by p75NTR.

Saxena S, Howe CL, Cosgaya JM, Hu M, Weis J, Krüttgen A. Saxena S, et al. Mol Cell Neurosci. 2004 Jun;26(2):292-307. doi: 10.1016/j.mcn.2004.02.006. Mol Cell Neurosci. 2004. PMID: 15207854

5

Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking.

Saxena S, Howe CL, Cosgaya JM, Steiner P, Hirling H, Chan JR, Weis J, Krüttgen A. Saxena S, et al. Mol Cell Neurosci. 2005 Mar;28(3):571-87. doi: 10.1016/j.mcn.2004.11.011. Mol Cell Neurosci. 2005. PMID: 15737746

6

The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA.

Saxena S, Bucci C, Weis J, Kruttgen A. Saxena S, et al. J Neurosci. 2005 Nov 23;25(47):10930-40. doi: 10.1523/JNEUROSCI.2029-05.2005. J Neurosci. 2005. PMID: 16306406 Free PMC article.

7

Proteasomal inhibition alters the trafficking of the neurotrophin receptor TrkA.

Moises T, Wüller S, Saxena S, Senderek J, Weis J, Krüttgen A. Moises T, et al. Among authors: saxena s. Biochem Biophys Res Commun. 2009 Sep 18;387(2):360-4. doi: 10.1016/j.bbrc.2009.07.032. Epub 2009 Jul 14. Biochem Biophys Res Commun. 2009. PMID: 19607811

8

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, Roos A, Troost D, Schneider BL, Weis J, Saxena S. Filézac de L'Etang A, et al. Among authors: saxena s. Nat Neurosci. 2015 Feb;18(2):227-38. doi: 10.1038/nn.3903. Epub 2015 Jan 5. Nat Neurosci. 2015. PMID: 25559081

9

Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.

Huo Q, Kayikci M, Odermatt P, Meyer K, Michels O, Saxena S, Ule J, Schümperli D. Huo Q, et al. Among authors: saxena s. RNA Biol. 2014;11(11):1430-46. doi: 10.1080/15476286.2014.996494. RNA Biol. 2014. PMID: 25692239 Free PMC article.

10

Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS.

Ruegsegger C, Maharjan N, Goswami A, Filézac de L'Etang A, Weis J, Troost D, Heller M, Gut H, Saxena S. Ruegsegger C, et al. Among authors: saxena s. Acta Neuropathol. 2016 Mar;131(3):427-51. doi: 10.1007/s00401-015-1510-4. Epub 2015 Nov 30. Acta Neuropathol. 2016. PMID: 26619836 Free article.

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