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Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health.
Stucki AO, Barton-Maclaren TS, Bhuller Y, Henriquez JE, Henry TR, Hirn C, Miller-Holt J, Nagy EG, Perron MM, Ratzlaff DE, Stedeford TJ, Clippinger AJ. Stucki AO, et al. Among authors: barton maclaren ts. Front Toxicol. 2022 Sep 1;4:964553. doi: 10.3389/ftox.2022.964553. eCollection 2022. Front Toxicol. 2022. PMID: 36119357 Free PMC article. Review.
From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow.
Reardon AJF, Farmahin R, Williams A, Meier MJ, Addicks GC, Yauk CL, Matteo G, Atlas E, Harrill J, Everett LJ, Shah I, Judson R, Ramaiahgari S, Ferguson SS, Barton-Maclaren TS. Reardon AJF, et al. Among authors: barton maclaren ts. Front Toxicol. 2023 May 23;5:1194895. doi: 10.3389/ftox.2023.1194895. eCollection 2023. Front Toxicol. 2023. PMID: 37288009 Free PMC article.
Accelerating the Pace of Chemical Risk Assessment.
Kavlock RJ, Bahadori T, Barton-Maclaren TS, Gwinn MR, Rasenberg M, Thomas RS. Kavlock RJ, et al. Chem Res Toxicol. 2018 May 21;31(5):287-290. doi: 10.1021/acs.chemrestox.7b00339. Epub 2018 Apr 6. Chem Res Toxicol. 2018. PMID: 29600706 Free PMC article. Review.
Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization.
Paul Friedman K, Gagne M, Loo LH, Karamertzanis P, Netzeva T, Sobanski T, Franzosa JA, Richard AM, Lougee RR, Gissi A, Lee JJ, Angrish M, Dorne JL, Foster S, Raffaele K, Bahadori T, Gwinn MR, Lambert J, Whelan M, Rasenberg M, Barton-Maclaren T, Thomas RS. Paul Friedman K, et al. Toxicol Sci. 2020 Jan 1;173(1):202-225. doi: 10.1093/toxsci/kfz201. Toxicol Sci. 2020. PMID: 31532525 Free PMC article.
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Johnson KJ, Auerbach SS, Stevens T, Barton-Maclaren TS, Costa E, Currie RA, Dalmas Wilk D, Haq S, Rager JE, Reardon AJF, Wehmas L, Williams A, O'Brien J, Yauk C, LaRocca JL, Pettit S. Johnson KJ, et al. Among authors: barton maclaren ts. Toxicol Sci. 2022 Nov 23;190(2):127-132. doi: 10.1093/toxsci/kfac097. Toxicol Sci. 2022. PMID: 36165699 Free PMC article.
38 results