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Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters.
Stewart A, Mayer FP, Gowrishankar R, Davis GL, Areal LB, Gresch PJ, Katamish RM, Peart R, Stilley SE, Spiess K, Rabil MJ, Diljohn FA, Wiggins AE, Vaughan RA, Hahn MK, Blakely RD. Stewart A, et al. Among authors: blakely rd. Mol Psychiatry. 2022 Dec;27(12):4869-4880. doi: 10.1038/s41380-022-01773-7. Epub 2022 Sep 18. Mol Psychiatry. 2022. PMID: 36117213
The functional impact of SLC6 transporter genetic variation.
Hahn MK, Blakely RD. Hahn MK, et al. Among authors: blakely rd. Annu Rev Pharmacol Toxicol. 2007;47:401-41. doi: 10.1146/annurev.pharmtox.47.120505.105242. Annu Rev Pharmacol Toxicol. 2007. PMID: 17067279 Review.
The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants.
Mergy MA, Gowrishankar R, Gresch PJ, Gantz SC, Williams J, Davis GL, Wheeler CA, Stanwood GD, Hahn MK, Blakely RD. Mergy MA, et al. Among authors: blakely rd. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4779-88. doi: 10.1073/pnas.1417294111. Epub 2014 Oct 20. Proc Natl Acad Sci U S A. 2014. PMID: 25331903 Free PMC article.
Blockade of the 5-HT transporter contributes to the behavioural, neuronal and molecular effects of cocaine.
Simmler LD, Anacker AMJ, Levin MH, Vaswani NM, Gresch PJ, Nackenoff AG, Anastasio NC, Stutz SJ, Cunningham KA, Wang J, Zhang B, Henry LK, Stewart A, Veenstra-VanderWeele J, Blakely RD. Simmler LD, et al. Among authors: blakely rd. Br J Pharmacol. 2017 Aug;174(16):2716-2738. doi: 10.1111/bph.13899. Epub 2017 Jul 11. Br J Pharmacol. 2017. PMID: 28585320 Free PMC article.
348 results