Sawaya MR - Search Results

1

Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.

Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS. Seidler PM, et al. Among authors: sawaya mr. Nat Commun. 2022 Sep 16;13(1):5451. doi: 10.1038/s41467-022-32951-4. Nat Commun. 2022. PMID: 36114178 Free PMC article.

2

The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core.

Mura C, Cascio D, Sawaya MR, Eisenberg DS. Mura C, et al. Among authors: sawaya mr. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5532-7. doi: 10.1073/pnas.091102298. Epub 2001 May 1. Proc Natl Acad Sci U S A. 2001. PMID: 11331747 Free PMC article.

3

Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets.

Wang S, Mura C, Sawaya MR, Cascio D, Eisenberg D. Wang S, et al. Among authors: sawaya mr. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):571-8. doi: 10.1107/s0907444902001191. Epub 2002 Mar 22. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11914479

4

Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD.

Goulding CW, Sawaya MR, Parseghian A, Lim V, Eisenberg D, Missiakas D. Goulding CW, et al. Among authors: sawaya mr. Biochemistry. 2002 Jun 4;41(22):6920-7. doi: 10.1021/bi016038l. Biochemistry. 2002. PMID: 12033924

5

Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution.

Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D. Goulding CW, et al. Among authors: sawaya mr. Protein Sci. 2002 Dec;11(12):2887-93. doi: 10.1110/ps.0219002. Protein Sci. 2002. PMID: 12441386 Free PMC article.

6

Granulysin crystal structure and a structure-derived lytic mechanism.

Anderson DH, Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D. Anderson DH, et al. Among authors: sawaya mr. J Mol Biol. 2003 Jan 10;325(2):355-65. doi: 10.1016/s0022-2836(02)01234-2. J Mol Biol. 2003. PMID: 12488100

7

Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA.

Goulding CW, Perry LJ, Anderson D, Sawaya MR, Cascio D, Apostol MI, Chan S, Parseghian A, Wang SS, Wu Y, Cassano V, Gill HS, Eisenberg D. Goulding CW, et al. Among authors: sawaya mr. Biophys Chem. 2003 Sep;105(2-3):361-70. doi: 10.1016/s0301-4622(03)00101-7. Biophys Chem. 2003. PMID: 14499904

8

Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning.

Lee S, Sawaya MR, Eisenberg D. Lee S, et al. Among authors: sawaya mr. Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2191-9. doi: 10.1107/s0907444903019942. Epub 2003 Nov 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 14646077

9

An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril.

Ivanova MI, Sawaya MR, Gingery M, Attinger A, Eisenberg D. Ivanova MI, et al. Among authors: sawaya mr. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10584-9. doi: 10.1073/pnas.0403756101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249659 Free PMC article.

10

The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase.

Müller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D. Müller P, et al. Among authors: sawaya mr. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. doi: 10.1107/S0907444904033190. Epub 2005 Feb 24. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 15735341

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