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Vaccination-based immunotherapy to target profibrotic cells in liver and lung.
Sobecki M, Chen J, Krzywinska E, Nagarajan S, Fan Z, Nelius E, Monné Rodriguez JM, Seehusen F, Hussein A, Moschini G, Hajam EY, Kiran R, Gotthardt D, Debbache J, Badoual C, Sato T, Isagawa T, Takeda N, Tanchot C, Tartour E, Weber A, Werner S, Loffing J, Sommer L, Sexl V, Münz C, Feghali-Bostwick C, Pachera E, Distler O, Snedeker J, Jamora C, Stockmann C. Sobecki M, et al. Among authors: distler o. Cell Stem Cell. 2022 Oct 6;29(10):1459-1474.e9. doi: 10.1016/j.stem.2022.08.012. Epub 2022 Sep 15. Cell Stem Cell. 2022. PMID: 36113462 Free article.
Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis.
Distler JH, Feghali-Bostwick C, Soare A, Asano Y, Distler O, Abraham DJ. Distler JH, et al. Among authors: distler o. Arthritis Rheumatol. 2017 Feb;69(2):257-267. doi: 10.1002/art.39865. Arthritis Rheumatol. 2017. PMID: 27636741 Free article. Review. No abstract available.
18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study.
Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, Vrugt B, Feghali-Bostwick C, Schibli R, Distler O, Müller C, Maurer B. Schniering J, et al. Among authors: distler o. Front Immunol. 2019 Nov 22;10:2724. doi: 10.3389/fimmu.2019.02724. eCollection 2019. Front Immunol. 2019. PMID: 31824505 Free PMC article.
Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis.
Pachera E, Assassi S, Salazar GA, Stellato M, Renoux F, Wunderlin A, Blyszczuk P, Lafyatis R, Kurreeman F, de Vries-Bouwstra J, Messemaker T, Feghali-Bostwick CA, Rogler G, van Haaften WT, Dijkstra G, Oakley F, Calcagni M, Schniering J, Maurer B, Distler JH, Kania G, Frank-Bertoncelj M, Distler O. Pachera E, et al. Among authors: distler jh, distler o. J Clin Invest. 2020 Sep 1;130(9):4888-4905. doi: 10.1172/JCI135439. J Clin Invest. 2020. PMID: 32603313 Free PMC article.
Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells.
Distler JH, Jüngel A, Caretto D, Schulze-Horsel U, Kowal-Bielecka O, Gay RE, Michel BA, Müller-Ladner U, Kalden JR, Gay S, Distler O. Distler JH, et al. Among authors: distler o. Arthritis Rheum. 2006 Jan;54(1):214-25. doi: 10.1002/art.21497. Arthritis Rheum. 2006. PMID: 16385517 Free article.
674 results