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Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
Zhao N, Qiao W, Li F, Ren Y, Zheng J, Martens YA, Wang X, Li L, Liu CC, Chen K, Zhu Y, Ikezu TC, Li Z, Meneses AD, Jin Y, Knight JA, Chen Y, Bastea L, Linares C, Sonustun B, Job L, Smith ML, Xie M, Liu YU, Umpierre AD, Haruwaka K, Quicksall ZS, Storz P, Asmann YW, Wu LJ, Bu G. Zhao N, et al. J Exp Med. 2022 Dec 5;219(12):e20212479. doi: 10.1084/jem.20212479. Epub 2022 Sep 15. J Exp Med. 2022. PMID: 36107206 Free PMC article.
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T. Shinohara M, et al. Among authors: zhao n. Acta Neuropathol. 2016 Aug;132(2):225-234. doi: 10.1007/s00401-016-1580-y. Epub 2016 May 14. Acta Neuropathol. 2016. PMID: 27179972 Free PMC article.
ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Liu CC, Zhao N, Fu Y, Wang N, Linares C, Tsai CW, Bu G. Liu CC, et al. Among authors: zhao n. Neuron. 2017 Dec 6;96(5):1024-1032.e3. doi: 10.1016/j.neuron.2017.11.013. Neuron. 2017. PMID: 29216449 Free PMC article.
APOE ε2 is associated with increased tau pathology in primary tauopathy.
Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, Caselli RJ, Sanchez-Contreras MY, Rademakers R, Murray ME, Koga S, Dickson DW, Ross OA, Bu G. Zhao N, et al. Nat Commun. 2018 Oct 22;9(1):4388. doi: 10.1038/s41467-018-06783-0. Nat Commun. 2018. PMID: 30348994 Free PMC article.
5,464 results