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Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains.
Sekirnik AR, Reynolds JK, See L, Bluck JP, Scorah AR, Tallant C, Lee B, Leszczynska KB, Grimley RL, Storer RI, Malattia M, Crespillo S, Caria S, Duclos S, Hammond EM, Knapp S, Morris GM, Duarte F, Biggin PC, Conway SJ. Sekirnik AR, et al. Among authors: leszczynska kb. ACS Chem Biol. 2022 Oct 21;17(10):2753-2768. doi: 10.1021/acschembio.2c00266. Epub 2022 Sep 13. ACS Chem Biol. 2022. PMID: 36098557 Free PMC article.
Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality.
Jiang Y, Verbiest T, Devery AM, Bokobza SM, Weber AM, Leszczynska KB, Hammond EM, Ryan AJ. Jiang Y, et al. Among authors: leszczynska kb. Int J Radiat Oncol Biol Phys. 2016 Jun 1;95(2):772-81. doi: 10.1016/j.ijrobp.2016.01.035. Epub 2016 Jan 23. Int J Radiat Oncol Biol Phys. 2016. PMID: 27020103 Free PMC article.
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication.
Foskolou IP, Jorgensen C, Leszczynska KB, Olcina MM, Tarhonskaya H, Haisma B, D'Angiolella V, Myers WK, Domene C, Flashman E, Hammond EM. Foskolou IP, et al. Among authors: leszczynska kb. Mol Cell. 2017 Apr 20;66(2):206-220.e9. doi: 10.1016/j.molcel.2017.03.005. Epub 2017 Apr 13. Mol Cell. 2017. PMID: 28416140 Free PMC article.
KDM4A regulates HIF-1 levels through H3K9me3.
Dobrynin G, McAllister TE, Leszczynska KB, Ramachandran S, Krieg AJ, Kawamura A, Hammond EM. Dobrynin G, et al. Among authors: leszczynska kb. Sci Rep. 2017 Sep 11;7(1):11094. doi: 10.1038/s41598-017-11658-3. Sci Rep. 2017. PMID: 28894274 Free PMC article.
28 results