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Aiming for the pocket.
Silvennoinen O, Haikarainen T, Virtanen A. Silvennoinen O, et al. Among authors: haikarainen t. Nat Chem Biol. 2022 Dec;18(12):1296-1297. doi: 10.1038/s41589-022-01120-5. Nat Chem Biol. 2022. PMID: 36097296 No abstract available.
Janus Kinases in Leukemia.
Raivola J, Haikarainen T, Abraham BG, Silvennoinen O. Raivola J, et al. Among authors: haikarainen t. Cancers (Basel). 2021 Feb 14;13(4):800. doi: 10.3390/cancers13040800. Cancers (Basel). 2021. PMID: 33672930 Free PMC article. Review.
Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain.
Virtanen AT, Haikarainen T, Sampathkumar P, Palmroth M, Liukkonen S, Liu J, Nekhotiaeva N, Hubbard SR, Silvennoinen O. Virtanen AT, et al. Among authors: haikarainen t. Pharmaceuticals (Basel). 2023 Jan 4;16(1):75. doi: 10.3390/ph16010075. Pharmaceuticals (Basel). 2023. PMID: 36678572 Free PMC article.
The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.
Saarikettu J, Lehmusvaara S, Pesu M, Junttila I, Partanen J, Sipilä P, Poutanen M, Yang J, Haikarainen T, Silvennoinen O. Saarikettu J, et al. Among authors: haikarainen t. FASEB Bioadv. 2023 Feb 21;5(5):183-198. doi: 10.1096/fba.2022-00115. eCollection 2023 May. FASEB Bioadv. 2023. PMID: 37151849 Free PMC article.
Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage.
Venkannagari H, Verheugd P, Koivunen J, Haikarainen T, Obaji E, Ashok Y, Narwal M, Pihlajaniemi T, Lüscher B, Lehtiö L. Venkannagari H, et al. Among authors: haikarainen t. Cell Chem Biol. 2016 Oct 20;23(10):1251-1260. doi: 10.1016/j.chembiol.2016.08.012. Epub 2016 Sep 22. Cell Chem Biol. 2016. PMID: 27667561 Free article.
47 results