Xu Y - Search Results

1

Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα.

Hart JR, Liu X, Pan C, Liang A, Ueno L, Xu Y, Quezada A, Zou X, Yang S, Zhou Q, Schoonooghe S, Hassanzadeh-Ghassabeh G, Xia T, Shui W, Yang D, Vogt PK, Wang MW. Hart JR, et al. Among authors: xu y. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2210769119. doi: 10.1073/pnas.2210769119. Epub 2022 Sep 12. Proc Natl Acad Sci U S A. 2022. PMID: 36095215 Free PMC article.

2

Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-α-cell axis.

Liu Q, Lin G, Chen Y, Feng W, Xu Y, Lyu J, Yang D, Wang MW. Liu Q, et al. Among authors: xu y. Biosci Rep. 2021 Jun 25;41(6):BSR20210758. doi: 10.1042/BSR20210758. Biosci Rep. 2021. PMID: 34002801 Free PMC article.

3

Cryo-EM structures of PI3Kα reveal conformational changes during inhibition and activation.

Liu X, Yang S, Hart JR, Xu Y, Zou X, Zhang H, Zhou Q, Xia T, Zhang Y, Yang D, Wang MW, Vogt PK. Liu X, et al. Among authors: xu y. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2109327118. doi: 10.1073/pnas.2109327118. Proc Natl Acad Sci U S A. 2021. PMID: 34725156 Free PMC article.

4

GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis.

Chen Y, Xu YN, Ye CY, Feng WB, Zhou QT, Yang DH, Wang MW. Chen Y, et al. Among authors: xu yn. Acta Pharmacol Sin. 2022 May;43(5):1156-1166. doi: 10.1038/s41401-021-00836-9. Epub 2021 Dec 21. Acta Pharmacol Sin. 2022. PMID: 34934197 Free PMC article. Review.

5

A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2.

Xu Y, Feng W, Zhou Q, Liang A, Li J, Dai A, Zhao F, Yan J, Chen CW, Li H, Zhao LH, Xia T, Jiang Y, Xu HE, Yang D, Wang MW. Xu Y, et al. Among authors: xu he. Nat Commun. 2022 Apr 27;13(1):2272. doi: 10.1038/s41467-022-30041-z. Nat Commun. 2022. PMID: 35477937 Free PMC article.

6

Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3Kα.

Liu X, Zhou Q, Hart JR, Xu Y, Yang S, Yang D, Vogt PK, Wang MW. Liu X, et al. Among authors: xu y. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2215621119. doi: 10.1073/pnas.2215621119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343266 Free PMC article.

7

Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.

Feng W, Zhou Q, Chen X, Dai A, Cai X, Liu X, Zhao F, Chen Y, Ye C, Xu Y, Cong Z, Li H, Lin S, Yang D, Wang MW. Feng W, et al. Among authors: xu y. Cell Discov. 2023 Jul 31;9(1):81. doi: 10.1038/s41421-023-00586-4. Cell Discov. 2023. PMID: 37524700 Free PMC article.

8

Molecular basis of signal transduction mediated by the human GIPR splice variants.

Zhao F, Hang K, Zhou Q, Shao L, Li H, Li W, Lin S, Dai A, Cai X, Liu Y, Xu Y, Feng W, Yang D, Wang MW. Zhao F, et al. Among authors: xu y. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2306145120. doi: 10.1073/pnas.2306145120. Epub 2023 Oct 4. Proc Natl Acad Sci U S A. 2023. PMID: 37792509 Free PMC article.

9

Absence of PNET formation and normal longevity in a mouse model of Mahvash disease.

Xu Y, Liu Q, Chen CW, Wang Q, Du T, Yu R, Zhou Q, Yang D, Wang MW. Xu Y, et al. Heliyon. 2024 Jul 26;10(15):e35362. doi: 10.1016/j.heliyon.2024.e35362. eCollection 2024 Aug 15. Heliyon. 2024. PMID: 39170309 Free PMC article.

10

Activity of crude extract of Rubus crataegifolius roots as a potent apoptosis inducer and DNA topoisomerase I inhibitor.

Lee JH, Ham YA, Choi SH, Im EO, Jung JH, Im KS, Kim DK, Xu Y, Wang MW, Kim ND. Lee JH, et al. Among authors: xu y. Arch Pharm Res. 2000 Aug;23(4):338-43. doi: 10.1007/BF02975444. Arch Pharm Res. 2000. PMID: 10976580

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