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P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.
Donald S, Humby T, Fyfe I, Segonds-Pichon A, Walker SA, Andrews SR, Coadwell WJ, Emson P, Wilkinson LS, Welch HC. Donald S, et al. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4483-8. doi: 10.1073/pnas.0712324105. Epub 2008 Mar 11. Proc Natl Acad Sci U S A. 2008. PMID: 18334636 Free PMC article.
PI3Kβ plays a critical role in neutrophil activation by immune complexes.
Kulkarni S, Sitaru C, Jakus Z, Anderson KE, Damoulakis G, Davidson K, Hirose M, Juss J, Oxley D, Chessa TA, Ramadani F, Guillou H, Segonds-Pichon A, Fritsch A, Jarvis GE, Okkenhaug K, Ludwig R, Zillikens D, Mocsai A, Vanhaesebroeck B, Stephens LR, Hawkins PT. Kulkarni S, et al. Sci Signal. 2011 Apr 12;4(168):ra23. doi: 10.1126/scisignal.2001617. Sci Signal. 2011. PMID: 21487106
Localizing the lipid products of PI3Kγ in neutrophils.
Norton L, Lindsay Y, Deladeriere A, Chessa T, Guillou H, Suire S, Lucocq J, Walker S, Andrews S, Segonds-Pichon A, Rausch O, Finan P, Sasaki T, Du CJ, Bretschneider T, Ferguson GJ, Hawkins PT, Stephens L. Norton L, et al. Adv Biol Regul. 2016 Jan;60:36-45. doi: 10.1016/j.jbior.2015.10.005. Epub 2015 Nov 10. Adv Biol Regul. 2016. PMID: 26596865 Free PMC article.
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection.
Pantarelli C, Pan D, Chetwynd S, Stark AK, Hornigold K, Machin P, Crossland L, Cleary SJ, Baker MJ, Hampson E, Mandel A, Segonds-Pichon A, Walker R, van 't Veer C, Riffo-Vasquez Y, Okkenhaug K, Pitchford S, Welch HCE. Pantarelli C, et al. Blood Adv. 2021 Aug 24;5(16):3076-3091. doi: 10.1182/bloodadvances.2020002782. Blood Adv. 2021. PMID: 34402884 Free PMC article.
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Machin PA, Johnsson AE, Massey EJ, Pantarelli C, Chetwynd SA, Chu JY, Okkenhaug H, Segonds-Pichon A, Walker S, Malliri A, Fukui Y, Welch HCE. Machin PA, et al. Among authors: segonds pichon a. Front Immunol. 2023 Jun 13;14:1180886. doi: 10.3389/fimmu.2023.1180886. eCollection 2023. Front Immunol. 2023. PMID: 37383235 Free PMC article.
43 results