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Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes.
Scoon WA, Mancio-Silva L, Suder EL, Villacorta-Martin C, Lindstrom-Vautrin J, Bernbaum JG, Mazur S, Johnson RF, Olejnik J, Flores EY, Mithal A, Wang F, Hume AJ, Kaserman JE, March-Riera S, Wilson AA, Bhatia SN, Mühlberger E, Mostoslavsky G. Scoon WA, et al. Among authors: wilson aa. Stem Cell Reports. 2022 Oct 11;17(10):2286-2302. doi: 10.1016/j.stemcr.2022.08.003. Epub 2022 Sep 8. Stem Cell Reports. 2022. PMID: 36084636 Free PMC article.
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.
Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, Lomas DA, Vallier L, Murphy GJ, Mostoslavsky G, Spira A, Shirihai OS, Ramirez MI, Gadue P, Kotton DN. Wilson AA, et al. Stem Cell Reports. 2015 May 12;4(5):873-85. doi: 10.1016/j.stemcr.2015.02.021. Epub 2015 Apr 2. Stem Cell Reports. 2015. PMID: 25843048 Free PMC article.
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency.
Segeritz CP, Rashid ST, de Brito MC, Serra MP, Ordonez A, Morell CM, Kaserman JE, Madrigal P, Hannan NRF, Gatto L, Tan L, Wilson AA, Lilley K, Marciniak SJ, Gooptu B, Lomas DA, Vallier L. Segeritz CP, et al. Among authors: wilson aa. J Hepatol. 2018 Oct;69(4):851-860. doi: 10.1016/j.jhep.2018.05.028. Epub 2018 Jun 5. J Hepatol. 2018. PMID: 29879455 Free PMC article.
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.
Hurley K, Ding J, Villacorta-Martin C, Herriges MJ, Jacob A, Vedaie M, Alysandratos KD, Sun YL, Lin C, Werder RB, Huang J, Wilson AA, Mithal A, Mostoslavsky G, Oglesby I, Caballero IS, Guttentag SH, Ahangari F, Kaminski N, Rodriguez-Fraticelli A, Camargo F, Bar-Joseph Z, Kotton DN. Hurley K, et al. Among authors: wilson aa. Cell Stem Cell. 2020 Apr 2;26(4):593-608.e8. doi: 10.1016/j.stem.2019.12.009. Epub 2020 Jan 30. Cell Stem Cell. 2020. PMID: 32004478 Free PMC article.
Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors.
Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Abo KM, et al. bioRxiv [Preprint]. 2020 Jun 4:2020.06.03.132639. doi: 10.1101/2020.06.03.132639. bioRxiv. 2020. PMID: 32577635 Free PMC article. Preprint.
A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.
Kaserman JE, Hurley K, Dodge M, Villacorta-Martin C, Vedaie M, Jean JC, Liberti DC, James MF, Higgins MI, Lee NJ, Washko GR, San Jose Estepar R, Teckman J, Kotton DN, Wilson AA. Kaserman JE, et al. Among authors: wilson aa. Stem Cell Reports. 2020 Jul 14;15(1):242-255. doi: 10.1016/j.stemcr.2020.06.006. Epub 2020 Jul 2. Stem Cell Reports. 2020. PMID: 32619491 Free PMC article.
SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. Huang J, et al. Among authors: wilson aa. bioRxiv [Preprint]. 2020 Aug 6:2020.06.30.175695. doi: 10.1101/2020.06.30.175695. bioRxiv. 2020. Update in: Cell Stem Cell. 2020 Dec 3;27(6):962-973.e7. doi: 10.1016/j.stem.2020.09.013 PMID: 32637964 Free PMC article. Updated. Preprint.
Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.
Giadone RM, Liberti DC, Matte TM, Rosarda JD, Torres-Arancivia C, Ghosh S, Diedrich JK, Pankow S, Skvir N, Jean JC, Yates JR 3rd, Wilson AA, Connors LH, Kotton DN, Wiseman RL, Murphy GJ. Giadone RM, et al. Among authors: wilson aa. Stem Cell Reports. 2020 Aug 11;15(2):515-528. doi: 10.1016/j.stemcr.2020.07.003. Epub 2020 Jul 30. Stem Cell Reports. 2020. PMID: 32735824 Free PMC article.
370 results