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Page 1
Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
Piacente F, Caffa I, Ravera S, Sociali G, Passalacqua M, Vellone VG, Becherini P, Reverberi D, Monacelli F, Ballestrero A, Odetti P, Cagnetta A, Cea M, Nahimana A, Duchosal M, Bruzzone S, Nencioni A. Piacente F, et al. Cancer Res. 2017 Jul 15;77(14):3857-3869. doi: 10.1158/0008-5472.CAN-16-3079. Epub 2017 May 15. Cancer Res. 2017. PMID: 28507103
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
Damonte P, Sociali G, Parenti MD, Soncini D, Bauer I, Boero S, Grozio A, Holtey MV, Piacente F, Becherini P, Sanguineti R, Salis A, Damonte G, Cea M, Murone M, Poggi A, Nencioni A, Del Rio A, Bruzzone S. Damonte P, et al. Among authors: piacente f. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858. doi: 10.1016/j.bmc.2017.09.023. Epub 2017 Sep 19. Bioorg Med Chem. 2017. PMID: 28958848
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice.
Becherini P, Caffa I, Piacente F, Damonte P, Vellone VG, Passalacqua M, Benzi A, Bonfiglio T, Reverberi D, Khalifa A, Ghanem M, Guijarro A, Tagliafico L, Sucameli M, Persia A, Monacelli F, Cea M, Bruzzone S, Ravera S, Nencioni A. Becherini P, et al. Among authors: piacente f. Cancer Metab. 2021 Jan 22;9(1):6. doi: 10.1186/s40170-021-00240-1. Cancer Metab. 2021. PMID: 33482921 Free PMC article.
Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery.
Ghanem MS, Caffa I, Del Rio A, Franco J, Parenti MD, Monacelli F, Cea M, Khalifa A, Nahimana A, Duchosal MA, Ravera S, Bertola N, Bruzzone S, Nencioni A, Piacente F. Ghanem MS, et al. Among authors: piacente f. Pharmaceuticals (Basel). 2022 Jul 10;15(7):848. doi: 10.3390/ph15070848. Pharmaceuticals (Basel). 2022. PMID: 35890147 Free PMC article.
Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors.
Franco J, Piacente F, Walter M, Fratta S, Ghanem M, Benzi A, Caffa I, Kurkin AV, Altieri A, Herr P, Martínez-Bailén M, Robina I, Bruzzone S, Nencioni A, Del Rio A. Franco J, et al. Among authors: piacente f. Pharmaceuticals (Basel). 2022 Jul 12;15(7):855. doi: 10.3390/ph15070855. Pharmaceuticals (Basel). 2022. PMID: 35890155 Free PMC article.
Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer.
Fratta S, Biniecka P, Moreno-Vargas AJ, Carmona AT, Nahimana A, Duchosal MA, Piacente F, Bruzzone S, Caffa I, Nencioni A, Robina I. Fratta S, et al. Among authors: piacente f. Eur J Med Chem. 2023 Mar 15;250:115170. doi: 10.1016/j.ejmech.2023.115170. Epub 2023 Jan 31. Eur J Med Chem. 2023. PMID: 36787658 Free article.
34 results