Kashlan OB - Search Results

1

Bile acids regulate the epithelial Na⁺ channel in native tissues through direct binding at multiple sites.

Wang XP, Tomilin V, Nickerson AJ, Tian R, Ertem M, McKernan A, Lei X, Pochynyuk O, Kashlan OB. Wang XP, et al. Among authors: kashlan ob. J Physiol. 2022 Nov;600(21):4695-4711. doi: 10.1113/JP283318. Epub 2022 Sep 23. J Physiol. 2022. PMID: 36071685 Free PMC article.

2

Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel.

Passero CJ, Carattino MD, Kashlan OB, Myerburg MM, Hughey RP, Kleyman TR. Passero CJ, et al. Among authors: kashlan ob. Am J Physiol Renal Physiol. 2010 Oct;299(4):F854-61. doi: 10.1152/ajprenal.00316.2010. Epub 2010 Jul 14. Am J Physiol Renal Physiol. 2010. PMID: 20630937 Free PMC article.

3

Epithelial Na⁺ Channel Regulation by Extracellular and Intracellular Factors.

Kleyman TR, Kashlan OB, Hughey RP. Kleyman TR, et al. Among authors: kashlan ob. Annu Rev Physiol. 2018 Feb 10;80:263-281. doi: 10.1146/annurev-physiol-021317-121143. Epub 2017 Nov 9. Annu Rev Physiol. 2018. PMID: 29120692 Free PMC article. Review.

4

N-linked glycans are required on epithelial Na⁺ channel subunits for maturation and surface expression.

Kashlan OB, Kinlough CL, Myerburg MM, Shi S, Chen J, Blobner BM, Buck TM, Brodsky JL, Hughey RP, Kleyman TR. Kashlan OB, et al. Am J Physiol Renal Physiol. 2018 Mar 1;314(3):F483-F492. doi: 10.1152/ajprenal.00195.2017. Epub 2017 Nov 29. Am J Physiol Renal Physiol. 2018. PMID: 29187368 Free PMC article.

5

Conserved cysteines in the finger domain of the epithelial Na⁺ channel α and γ subunits are proximal to the dynamic finger-thumb domain interface.

Blobner BM, Wang XP, Kashlan OB. Blobner BM, et al. Among authors: kashlan ob. J Biol Chem. 2018 Mar 30;293(13):4928-4939. doi: 10.1074/jbc.M117.819367. Epub 2018 Feb 7. J Biol Chem. 2018. PMID: 29425099 Free PMC article.

6

Murine epithelial sodium (Na⁺) channel regulation by biliary factors.

Wang XP, Im SJ, Balchak DM, Montalbetti N, Carattino MD, Ray EC, Kashlan OB. Wang XP, et al. Among authors: kashlan ob. J Biol Chem. 2019 Jun 28;294(26):10182-10193. doi: 10.1074/jbc.RA119.007394. Epub 2019 May 15. J Biol Chem. 2019. PMID: 31092599 Free PMC article.

7

Activation by cleavage of the epithelial Na⁺ channel α and γ subunits independently coevolved with the vertebrate terrestrial migration.

Wang XP, Balchak DM, Gentilcore C, Clark NL, Kashlan OB. Wang XP, et al. Among authors: kashlan ob. Elife. 2022 Jan 5;11:e75796. doi: 10.7554/eLife.75796. Elife. 2022. PMID: 34984981 Free PMC article.

8

Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced channel activity.

Nickerson AJ, Mutchler SM, Sheng S, Cox NA, Ray EC, Kashlan OB, Carattino MD, Marciszyn AL, Winfrey A, Gingras S, Kirabo A, Hughey RP, Kleyman TR. Nickerson AJ, et al. Among authors: kashlan ob. JCI Insight. 2023 Nov 8;8(21):e172051. doi: 10.1172/jci.insight.172051. JCI Insight. 2023. PMID: 37707951 Free PMC article.

9

Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice.

Wang XP, Mutchler SM, Carrisoza-Gáytan R, Al-Bataineh M, Baty CJ, Vandevender A, Srinivasan P, Tan RJ, Jurczak MJ, Satlin LM, Kashlan OB. Wang XP, et al. Among authors: kashlan ob. bioRxiv [Preprint]. 2023 Sep 22:2023.09.19.558474. doi: 10.1101/2023.09.19.558474. bioRxiv. 2023. Update in: J Am Soc Nephrol. 2024 Nov 1;35(11):1466-1477. doi: 10.1681/ASN.0000000000000442 PMID: 37790468 Free PMC article. Updated. Preprint.

10

MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport.

Farrell CE, Liu X, Yagan NO, Suda AC, Cerqueira DM, Bodnar AJ, Kashlan OB, Subramanya AR, Ho J, Butterworth MB. Farrell CE, et al. Among authors: kashlan ob. Am J Physiol Cell Physiol. 2024 Jan 1;326(1):C282-C293. doi: 10.1152/ajpcell.00385.2023. Epub 2023 Dec 4. Am J Physiol Cell Physiol. 2024. PMID: 38047299 Free PMC article.

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