Stetson DB - Search Results

1

ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP.

Maltbaek JH, Cambier S, Snyder JM, Stetson DB. Maltbaek JH, et al. Among authors: stetson db. Immunity. 2022 Oct 11;55(10):1799-1812.e4. doi: 10.1016/j.immuni.2022.08.006. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070769 Free PMC article.

2

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease.

Gall A, Treuting P, Elkon KB, Loo YM, Gale M Jr, Barber GN, Stetson DB. Gall A, et al. Among authors: stetson db. Immunity. 2012 Jan 27;36(1):120-31. doi: 10.1016/j.immuni.2011.11.018. Immunity. 2012. PMID: 22284419 Free PMC article.

3

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.

Gray EE, Treuting PM, Woodward JJ, Stetson DB. Gray EE, et al. Among authors: stetson db. J Immunol. 2015 Sep 1;195(5):1939-43. doi: 10.4049/jimmunol.1500969. Epub 2015 Jul 29. J Immunol. 2015. PMID: 26223655 Free PMC article.

4

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.

Pestal K, Funk CC, Snyder JM, Price ND, Treuting PM, Stetson DB. Pestal K, et al. Among authors: stetson db. Immunity. 2015 Nov 17;43(5):933-44. doi: 10.1016/j.immuni.2015.11.001. Immunity. 2015. PMID: 26588779 Free PMC article.

5

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

Gray EE, Winship D, Snyder JM, Child SJ, Geballe AP, Stetson DB. Gray EE, et al. Among authors: stetson db. Immunity. 2016 Aug 16;45(2):255-66. doi: 10.1016/j.immuni.2016.06.015. Epub 2016 Aug 2. Immunity. 2016. PMID: 27496731 Free PMC article.

6

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.

Volkman HE, Cambier S, Gray EE, Stetson DB. Volkman HE, et al. Among authors: stetson db. Elife. 2019 Dec 6;8:e47491. doi: 10.7554/eLife.47491. Elife. 2019. PMID: 31808743 Free PMC article.

7

Human DNA-PK activates a STING-independent DNA sensing pathway.

Burleigh K, Maltbaek JH, Cambier S, Green R, Gale M Jr, James RC, Stetson DB. Burleigh K, et al. Among authors: stetson db. Sci Immunol. 2020 Jan 24;5(43):eaba4219. doi: 10.1126/sciimmunol.aba4219. Sci Immunol. 2020. PMID: 31980485 Free PMC article.

8

Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.

Maurano M, Snyder JM, Connelly C, Henao-Mejia J, Sidrauski C, Stetson DB. Maurano M, et al. Among authors: stetson db. Immunity. 2021 Sep 14;54(9):1948-1960.e5. doi: 10.1016/j.immuni.2021.07.001. Epub 2021 Aug 2. Immunity. 2021. PMID: 34343497 Free PMC article.

9

ADAR1 mutation causes ZBP1-dependent immunopathology.

Hubbard NW, Ames JM, Maurano M, Chu LH, Somfleth KY, Gokhale NS, Werner M, Snyder JM, Lichauco K, Savan R, Stetson DB, Oberst A. Hubbard NW, et al. Among authors: stetson db. Nature. 2022 Jul;607(7920):769-775. doi: 10.1038/s41586-022-04896-7. Epub 2022 Jul 20. Nature. 2022. PMID: 35859177 Free PMC article.

10

Computational design of constitutively active cGAS.

Dowling QM, Volkman HE, Gray EE, Ovchinnikov S, Cambier S, Bera AK, Sankaran B, Johnson MR, Bick MJ, Kang A, Stetson DB, King NP. Dowling QM, et al. Among authors: stetson db. Nat Struct Mol Biol. 2023 Jan;30(1):72-80. doi: 10.1038/s41594-022-00862-z. Epub 2023 Jan 2. Nat Struct Mol Biol. 2023. PMID: 36593311

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