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Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units.
Love SB, Cafferty F, Snowdon C, Carty K, Savage J, Pallmann P, McParland L, Brown L, Masters L, Schiavone F, Hague D, Townsend S, Amos C, South A, Sturgeon K, Langley R, Maughan T, James N, Hall E, Kernaghan S, Bliss J, Turner N, Tutt A, Yap C, Firth C, Kong A, Mehanna H, Watts C, Hills R, Thomas I, Copland M, Bell S, Sebag-Montefiore D, Jones R, Parmar MKB, Sydes MR. Love SB, et al. Among authors: kong a. Trials. 2022 Sep 6;23(1):757. doi: 10.1186/s13063-022-06680-4. Trials. 2022. PMID: 36068599 Free PMC article.
Concurrent cisplatin or cetuximab with radiotherapy for HPV-positive oropharyngeal cancer: Medical resource use, costs, and quality-adjusted survival from the De-ESCALaTE HPV trial.
Jones DA, Mistry P, Dalby M, Fulton-Lieuw T, Kong AH, Dunn J, Mehanna HM, Gray AM. Jones DA, et al. Among authors: kong ah. Eur J Cancer. 2020 Jan;124:178-185. doi: 10.1016/j.ejca.2019.10.025. Epub 2019 Nov 30. Eur J Cancer. 2020. PMID: 31794928 Free PMC article. Clinical Trial.
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol.
Kong A, Good J, Kirkham A, Savage J, Mant R, Llewellyn L, Parish J, Spruce R, Forster M, Schipani S, Harrington K, Sacco J, Murray P, Middleton G, Yap C, Mehanna H. Kong A, et al. BMJ Open. 2020 Mar 16;10(3):e033009. doi: 10.1136/bmjopen-2019-033009. BMJ Open. 2020. PMID: 32184305 Free PMC article. Clinical Trial.
WEE1 Inhibitor: Clinical Development.
Kong A, Mehanna H. Kong A, et al. Curr Oncol Rep. 2021 Jul 16;23(9):107. doi: 10.1007/s11912-021-01098-8. Curr Oncol Rep. 2021. PMID: 34269904 Free PMC article. Review.
CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer.
Mehanna H, Gaunt P, Kong A, Hartley A, Sanghera P, Forster M, Sen M, Paleri V, Fong C, Geropantas D, Srinivasan D, Garikipati S, Moleron R, Casswell G, Aynsley E, Ward A, O'Toole L, Mirza A, Firth C, Humphreys I, Fulton-Lieuw T, Roques T, Nankivell P. Mehanna H, et al. Among authors: kong a. Trials. 2024 Jan 15;25(1):50. doi: 10.1186/s13063-023-07881-1. Trials. 2024. PMID: 38221636 Free PMC article.
1,773 results