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Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.
Orsini F, Villa P, Parrella S, Zangari R, Zanier ER, Gesuete R, Stravalaci M, Fumagalli S, Ottria R, Reina JJ, Paladini A, Micotti E, Ribeiro-Viana R, Rojo J, Pavlov VI, Stahl GL, Bernardi A, Gobbi M, De Simoni MG. Orsini F, et al. Among authors: fumagalli s. Circulation. 2012 Sep 18;126(12):1484-94. doi: 10.1161/CIRCULATIONAHA.112.103051. Epub 2012 Aug 9. Circulation. 2012. PMID: 22879370 Free PMC article.
Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury.
De Blasio D, Fumagalli S, Longhi L, Orsini F, Palmioli A, Stravalaci M, Vegliante G, Zanier ER, Bernardi A, Gobbi M, De Simoni MG. De Blasio D, et al. Among authors: fumagalli s. J Cereb Blood Flow Metab. 2017 Mar;37(3):938-950. doi: 10.1177/0271678X16647397. Epub 2016 Jul 20. J Cereb Blood Flow Metab. 2017. PMID: 27165013 Free PMC article.
Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy.
Filipe A, Chernorudskiy A, Arbogast S, Varone E, Villar-Quiles RN, Pozzer D, Moulin M, Fumagalli S, Cabet E, Dudhal S, De Simoni MG, Denis R, Vadrot N, Dill C, Giovarelli M, Szweda L, De Palma C, Pinton P, Giorgi C, Viscomi C, Clementi E, Missiroli S, Boncompagni S, Zito E, Ferreiro A. Filipe A, et al. Among authors: fumagalli s. Cell Death Differ. 2021 Jan;28(1):123-138. doi: 10.1038/s41418-020-0587-z. Epub 2020 Jul 13. Cell Death Differ. 2021. PMID: 32661288 Free PMC article.
Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity.
Chernorudskiy A, Varone E, Colombo SF, Fumagalli S, Cagnotto A, Cattaneo A, Briens M, Baltzinger M, Kuhn L, Bachi A, Berardi A, Salmona M, Musco G, Borgese N, Lescure A, Zito E. Chernorudskiy A, et al. Among authors: fumagalli s. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21288-21298. doi: 10.1073/pnas.2003847117. Epub 2020 Aug 17. Proc Natl Acad Sci U S A. 2020. PMID: 32817544 Free PMC article.
Functional organization of the endoplasmic reticulum dictates the susceptibility of target cells to arsenite-induced mitochondrial superoxide formation, mitochondrial dysfunction and apoptosis.
Guidarelli A, Catalani A, Spina A, Varone E, Fumagalli S, Zito E, Fiorani M, Cantoni O. Guidarelli A, et al. Among authors: fumagalli s. Food Chem Toxicol. 2021 Oct;156:112523. doi: 10.1016/j.fct.2021.112523. Epub 2021 Aug 25. Food Chem Toxicol. 2021. PMID: 34453993
300 results