Wolfe AL - Search Results

1

Total synthesis and antibacterial evaluation of Empetroxepins A and B and related analogs.

Murphy KE, Thacher MK, Young EC, Mojik V, Wolfe AL. Murphy KE, et al. Among authors: wolfe al. Bioorg Med Chem Lett. 2022 Nov 1;75:128955. doi: 10.1016/j.bmcl.2022.128955. Epub 2022 Aug 26. Bioorg Med Chem Lett. 2022. PMID: 36038118

2

Isolation of the antibiotic pseudopyronine B and SAR evaluation of C3/C6 alkyl analogs.

Bouthillette LM, Darcey CA, Handy TE, Seaton SC, Wolfe AL. Bouthillette LM, et al. Among authors: wolfe al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2762-2765. doi: 10.1016/j.bmcl.2017.04.067. Epub 2017 Apr 23. Bioorg Med Chem Lett. 2017. PMID: 28478925

3

Short chain α-pyrones capable of potentiating penicillin G against Pseudomonas aeruginosa.

Fields L, Craig WR, Huffine CA, Allen CF, Bouthillette LM, Chappell JC, Shumate JT, Wolfe AL. Fields L, et al. Among authors: wolfe al. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127301. doi: 10.1016/j.bmcl.2020.127301. Epub 2020 Jun 2. Bioorg Med Chem Lett. 2020. PMID: 32631521

4

Advances in antibiotic drug discovery: reducing the barriers for antibiotic development.

Murphy KE, Sloan GF, Lawhern GV, Volk GE, Shumate JT, Wolfe AL. Murphy KE, et al. Among authors: wolfe al. Future Med Chem. 2020 Nov;12(22):2067-2087. doi: 10.4155/fmc-2020-0247. Epub 2020 Oct 30. Future Med Chem. 2020. PMID: 33124460 Review.

5

Design and evaluation of poly-nitrogenous adjuvants capable of potentiating antibiotics in Gram-negative bacteria.

Pugh BA, Rao AB, Angeles-Solano M, Grosser MR, Brock JW, Murphy KE, Wolfe AL. Pugh BA, et al. Among authors: wolfe al. RSC Med Chem. 2022 Jul 6;13(9):1058-1063. doi: 10.1039/d2md00041e. eCollection 2022 Sep 21. RSC Med Chem. 2022. PMID: 36324495 Free PMC article.

6

Amine Basicity of Quinoline ATP Synthase Inhibitors Drives Antibacterial Activity against Pseudomonas aeruginosa.

Ward KT, Williams APL, Blair CA, Chatterjee AM, Karthikeyan A, Roper AS, Kellogg CN, Steed PR, Wolfe AL. Ward KT, et al. Among authors: wolfe al. ACS Med Chem Lett. 2023 Dec 26;15(1):149-155. doi: 10.1021/acsmedchemlett.3c00480. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229742 Free PMC article.

7

Synthesis and characterization of water-soluble free-base, zinc and copper porphyrin-oligonucleotide conjugates.

Mammana A, Asakawa T, Bitsch-Jensen K, Wolfe A, Chaturantabut S, Otani Y, Li X, Li Z, Nakanishi K, Balaz M, Ellestad GA, Berova N. Mammana A, et al. Bioorg Med Chem. 2008 Jul 1;16(13):6544-51. doi: 10.1016/j.bmc.2008.05.041. Epub 2008 May 21. Bioorg Med Chem. 2008. PMID: 18524599

8

Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study.

Ballard TE, Richards JJ, Wolfe AL, Melander C. Ballard TE, et al. Among authors: wolfe al. Chemistry. 2008;14(34):10745-61. doi: 10.1002/chem.200801419. Chemistry. 2008. PMID: 18942682

9

Total synthesis of kopsinine.

Xie J, Wolfe AL, Boger DL. Xie J, et al. Among authors: wolfe al. Org Lett. 2013 Feb 15;15(4):868-70. doi: 10.1021/ol303573f. Epub 2013 Feb 7. Org Lett. 2013. PMID: 23391149 Free PMC article.

10

A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding.

Wolfe AL, Duncan KK, Lajiness JP, Zhu K, Duerfeldt AS, Boger DL. Wolfe AL, et al. J Med Chem. 2013 Sep 12;56(17):6845-57. doi: 10.1021/jm400665c. Epub 2013 Aug 29. J Med Chem. 2013. PMID: 23944748 Free PMC article.

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