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In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.
le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL, Labesse G. le Maire A, et al. Among authors: gelin m. Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):747-55. doi: 10.1107/S0907444911023249. Epub 2011 Aug 9. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21904027
Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Lecointre C, Simon V, Kerneur C, Allemand F, Fournet A, Montarras I, Pons JL, Gelin M, Brignatz C, Urbach S, Labesse G, Roche S. Lecointre C, et al. Among authors: gelin m. Structure. 2018 Apr 3;26(4):545-554.e4. doi: 10.1016/j.str.2018.01.017. Epub 2018 Mar 1. Structure. 2018. PMID: 29503074 Free article.
First-in-class allosteric inhibitors of bacterial IMPDHs.
Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugué L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H. Alexandre T, et al. Among authors: gelin m. Eur J Med Chem. 2019 Apr 1;167:124-132. doi: 10.1016/j.ejmech.2019.01.064. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30769241 Free article.
297 results