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Seeding-competent TDP-43 persists in human patient and mouse muscle.
Lynch EM, Pittman S, Daw J, Ikenaga C, Chen S, Dhavale DD, Jackrel ME, Ayala YM, Kotzbauer P, Ly CV, Pestronk A, Lloyd TE, Weihl CC. Lynch EM, et al. Among authors: ayala ym. Sci Transl Med. 2024 Nov 27;16(775):eadp5730. doi: 10.1126/scitranslmed.adp5730. Epub 2024 Nov 27. Sci Transl Med. 2024. PMID: 39602508
Structural details of helix-mediated TDP-43 C-terminal domain multimerization.
Rizuan A, Shenoy J, Mohanty P, Dos Passos PMS, Mercado Ortiz JF, Bai L, Viswanathan R, Wang SH, Johnson V, Mamede LD, Ayala YM, Ghirlando R, Mittal J, Fawzi NL. Rizuan A, et al. Among authors: ayala ym. bioRxiv [Preprint]. 2024 Jul 5:2024.07.05.602258. doi: 10.1101/2024.07.05.602258. bioRxiv. 2024. PMID: 39005345 Free PMC article. Preprint.
Seeding competent TDP-43 persists in human patient and mouse muscle.
Lynch EM, Pittman S, Daw J, Ikenaga C, Chen S, Dhavale DD, Jackrel ME, Ayala YM, Kotzbauer P, Ly CV, Pestronk A, Lloyd TE, Weihl CC. Lynch EM, et al. Among authors: ayala ym. bioRxiv [Preprint]. 2024 Apr 4:2024.04.03.587918. doi: 10.1101/2024.04.03.587918. bioRxiv. 2024. Update in: Sci Transl Med. 2024 Nov 27;16(775):eadp5730. doi: 10.1126/scitranslmed.adp5730 PMID: 38617354 Free PMC article. Updated. Preprint.
Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration.
Dermentzaki G, Furlan M, Tanaka I, Leonardi T, Rinchetti P, Passos PMS, Bastos A, Ayala YM, Hanna JH, Przedborski S, Bonanomi D, Pelizzola M, Lotti F. Dermentzaki G, et al. Among authors: ayala ym. Cell Rep. 2024 Apr 23;43(4):113999. doi: 10.1016/j.celrep.2024.113999. Epub 2024 Mar 30. Cell Rep. 2024. PMID: 38554281 Free PMC article.
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates.
Yan X, Kuster D, Mohanty P, Nijssen J, Pombo-García K, Rizuan A, Franzmann TM, Sergeeva A, Passos PM, George L, Wang SH, Shenoy J, Danielson HL, Honigmann A, Ayala YM, Fawzi NL, Mittal J, Alberti S, Hyman AA. Yan X, et al. Among authors: ayala ym. bioRxiv [Preprint]. 2024 May 24:2024.01.23.576837. doi: 10.1101/2024.01.23.576837. bioRxiv. 2024. PMID: 38328053 Free PMC article. Preprint.
Role of BicDR in bristle shaft construction and support of BicD functions.
Jejina A, Ayala Y, Beuchle D, Höhener T, Dörig RE, Vazquez-Pianzola P, Hernández G, Suter B. Jejina A, et al. Among authors: ayala y. J Cell Sci. 2024 Jan 15;137(2):jcs261408. doi: 10.1242/jcs.261408. Epub 2024 Jan 31. J Cell Sci. 2024. PMID: 38264934 Free PMC article.
The gene expression signature of electrical stimulation in the human brain.
Chatterjee S, Vanrobaeys Y, Gleason AI, Park BJ, Heiney SA, Rhone AE, Nourski KV, Langmack L, Basu B, Mukherjee U, Kovach CK, Kocsis Z, Kikuchi Y, Ayala YA, Petkov CI, Hefti MM, Bahl E, Michaelson JJ, Kawasaki H, Oya H, Howard MA 3rd, Nickl-Jockschat T, Lin LC, Abel T. Chatterjee S, et al. Among authors: ayala ya. bioRxiv [Preprint]. 2024 Oct 22:2023.09.21.558812. doi: 10.1101/2023.09.21.558812. bioRxiv. 2024. PMID: 37790527 Free PMC article. Preprint.
74 results