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PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.
Toskas K, Yaghmaeian-Salmani B, Skiteva O, Paslawski W, Gillberg L, Skara V, Antoniou I, Södersten E, Svenningsson P, Chergui K, Ringnér M, Perlmann T, Holmberg J. Toskas K, et al. Among authors: perlmann t. Sci Adv. 2022 Aug 26;8(34):eabo1543. doi: 10.1126/sciadv.abo1543. Epub 2022 Aug 26. Sci Adv. 2022. PMID: 36026451 Free PMC article.
Maintaining differentiated cellular identity.
Holmberg J, Perlmann T. Holmberg J, et al. Among authors: perlmann t. Nat Rev Genet. 2012 May 18;13(6):429-39. doi: 10.1038/nrg3209. Nat Rev Genet. 2012. PMID: 22596319 Review.
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.
Kadkhodaei B, Alvarsson A, Schintu N, Ramsköld D, Volakakis N, Joodmardi E, Yoshitake T, Kehr J, Decressac M, Björklund A, Sandberg R, Svenningsson P, Perlmann T. Kadkhodaei B, et al. Among authors: perlmann t. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2360-5. doi: 10.1073/pnas.1221077110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341612 Free PMC article.
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gómez-Galán M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T. Laguna A, et al. Among authors: perlmann t. Nat Neurosci. 2015 Jun;18(6):826-35. doi: 10.1038/nn.4004. Epub 2015 Apr 27. Nat Neurosci. 2015. PMID: 25915474
121 results