Wang N - Search Results

1

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Liu W, Wu L, Liu W, Tian L, Chen H, Wu Z, Wang N, Liu X, Qiu J, Feng X, Xu Z, Jiang X, Zhao Q. Liu W, et al. Among authors: wang n. Eur J Med Chem. 2022 Nov 15;242:114689. doi: 10.1016/j.ejmech.2022.114689. Epub 2022 Aug 19. Eur J Med Chem. 2022. PMID: 36007469

2

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease.

Liu W, Liu X, Liu W, Gao Y, Wu L, Huang Y, Chen H, Li D, Zhou L, Wang N, Xu Z, Jiang X, Zhao Q. Liu W, et al. Among authors: wang n. Eur J Med Chem. 2022 Feb 5;229:114095. doi: 10.1016/j.ejmech.2021.114095. Epub 2021 Dec 30. Eur J Med Chem. 2022. PMID: 34995924

3

Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer.

Wu L, Liu W, Huang Y, Zhu C, Ma Q, Wu Q, Tian L, Feng X, Liu M, Wang N, Xu X, Liu X, Xu C, Qiu J, Xu Z, Liu W, Zhao Q. Wu L, et al. Among authors: wang n. Eur J Med Chem. 2022 Nov 15;242:114701. doi: 10.1016/j.ejmech.2022.114701. Epub 2022 Aug 28. Eur J Med Chem. 2022. PMID: 36054949

4

Design, Synthesis, and Biological Evaluation of Notopterol Derivatives as Triple Inhibitors of AChE/BACE1/GSK3β for the Treatment of Alzheimer's Disease.

Wang N, Liu W, Zhou L, Liu W, Liang X, Liu X, Xu Z, Zhong T, Wu Q, Jiao X, Chen J, Ning X, Jiang X, Zhao Q. Wang N, et al. ACS Omega. 2022 Aug 30;7(36):32131-32152. doi: 10.1021/acsomega.2c03368. eCollection 2022 Sep 13. ACS Omega. 2022. PMID: 36120034 Free PMC article.

5

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment.

Liu W, Tian L, Wu L, Chen H, Wang N, Liu X, Zhao C, Wu Z, Jiang X, Wu Q, Xu Z, Liu W, Zhao Q. Liu W, et al. Among authors: wang n. Bioorg Chem. 2022 Dec;129:106168. doi: 10.1016/j.bioorg.2022.106168. Epub 2022 Sep 28. Bioorg Chem. 2022. PMID: 36191431

6

Yuan-Zhi decoction in the treatment of Alzheimer's disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation.

Wu Q, Li X, Jiang XW, Yao D, Zhou LJ, Xu ZH, Wang N, Zhao QC, Zhang Z. Wu Q, et al. Among authors: wang n. Front Pharmacol. 2022 Aug 24;13:893244. doi: 10.3389/fphar.2022.893244. eCollection 2022. Front Pharmacol. 2022. PMID: 36091836 Free PMC article.

7

An integrated multi-omics approach revealed the regulation of melatonin on age-dependent mitochondrial function impair and lipid dyshomeostasis in mice hippocampus.

Jiang X, Xu Z, Yao D, Liu X, Liu W, Wang N, Li X, Diao Y, Zhang Y, Zhao Q. Jiang X, et al. Among authors: wang n. Pharmacol Res. 2022 May;179:106210. doi: 10.1016/j.phrs.2022.106210. Epub 2022 Apr 7. Pharmacol Res. 2022. PMID: 35398524

8

Identification of New Potent Human Uncoupling Protein 1 (UCP1) Agonists Using Virtual Screening and in vitro Approaches.

Lu HY, Wang N, Li X, Huang Y, Wang J, Zhao QC. Lu HY, et al. Among authors: wang j, wang n. Mol Inform. 2019 Oct;38(10):e1900030. doi: 10.1002/minf.201900030. Epub 2019 Jul 2. Mol Inform. 2019. PMID: 31264791

9

Notopterygium incisum Root Extract (NRE) Alleviates Epileptiform Symptoms in PTZ-Induced Acute Seizure Mice.

Zhou L, Gao Y, Lu H, Liu W, Xu X, Xing B, Liang X, Wang N, Jiang X, Zhao Q. Zhou L, et al. Among authors: wang n. CNS Neurol Disord Drug Targets. 2023;22(5):774-783. doi: 10.2174/1871527321666220406111745. CNS Neurol Disord Drug Targets. 2023. PMID: 35388767

10

Atractylenolide III from Atractylodes macrocephala Koidz promotes the activation of brown and white adipose tissue through SIRT1/PGC-1α signaling pathway.

Liu X, Huang Y, Liang X, Wu Q, Wang N, Zhou LJ, Liu WW, Ma Q, Hu B, Gao H, Cui YL, Li X, Zhao QC. Liu X, et al. Among authors: wang n. Phytomedicine. 2022 Sep;104:154289. doi: 10.1016/j.phymed.2022.154289. Epub 2022 Jun 26. Phytomedicine. 2022. PMID: 35785561

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