Liu X - Search Results

1

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Liu W, Wu L, Liu W, Tian L, Chen H, Wu Z, Wang N, Liu X, Qiu J, Feng X, Xu Z, Jiang X, Zhao Q. Liu W, et al. Among authors: liu x. Eur J Med Chem. 2022 Nov 15;242:114689. doi: 10.1016/j.ejmech.2022.114689. Epub 2022 Aug 19. Eur J Med Chem. 2022. PMID: 36007469

2

Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.

Chen X, Zhan P, Liu X, Cheng Z, Meng C, Shao S, Pannecouque C, De Clercq E, Liu X. Chen X, et al. Among authors: liu x. Bioorg Med Chem. 2012 Jun 15;20(12):3856-64. doi: 10.1016/j.bmc.2012.04.030. Epub 2012 Apr 21. Bioorg Med Chem. 2012. PMID: 22591854

3

Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.

Cao X, Zhang Y, Chen Y, Qiu Y, Yu M, Xu X, Liu X, Liu BF, Zhang L, Zhang G. Cao X, et al. Among authors: liu x, liu bf. J Med Chem. 2018 Nov 21;61(22):10017-10039. doi: 10.1021/acs.jmedchem.8b01096. Epub 2018 Nov 9. J Med Chem. 2018. PMID: 30383372

4

Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.

Xiong J, Jin J, Gao L, Hao C, Liu X, Liu BF, Chen Y, Zhang G. Xiong J, et al. Among authors: liu x, liu bf. Eur J Med Chem. 2020 Apr 1;191:112144. doi: 10.1016/j.ejmech.2020.112144. Epub 2020 Feb 14. Eur J Med Chem. 2020. PMID: 32087465

5

Isoquinolinone derivatives as potent CNS multi-receptor D₂/5-HT_1A/5-HT_2A/5-HT₆/5-HT₇ agents: Synthesis and pharmacological evaluation.

Jin J, Zhang K, Dou F, Hao C, Zhang Y, Cao X, Gao L, Xiong J, Liu X, Liu BF, Zhang G, Chen Y. Jin J, et al. Among authors: liu x, liu bf. Eur J Med Chem. 2020 Dec 1;207:112709. doi: 10.1016/j.ejmech.2020.112709. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32877805

6

PROTACs suppression of GSK-3β, a crucial kinase in neurodegenerative diseases.

Jiang X, Zhou J, Wang Y, Liu X, Xu K, Xu J, Feng F, Sun H. Jiang X, et al. Among authors: liu x. Eur J Med Chem. 2021 Jan 15;210:112949. doi: 10.1016/j.ejmech.2020.112949. Epub 2020 Oct 17. Eur J Med Chem. 2021. PMID: 33097303

7

Arctium lappa L. roots ameliorates cerebral ischemia through inhibiting neuronal apoptosis and suppressing AMPK/mTOR-mediated autophagy.

Yang Y, Gao H, Liu W, Liu X, Jiang X, Li X, Wu Q, Xu Z, Zhao Q. Yang Y, et al. Among authors: liu x, liu w. Phytomedicine. 2021 May;85:153526. doi: 10.1016/j.phymed.2021.153526. Epub 2021 Feb 21. Phytomedicine. 2021. PMID: 33691269

8

Discovery of a new class of multi-target heterocycle piperidine derivatives as potential antipsychotics with pro-cognitive effect.

Gao L, Hao C, Chen J, Ma R, Zheng L, Wu Q, Liu X, Liu BF, Zhang G, Chen Y, Jin J. Gao L, et al. Among authors: liu x, liu bf. Bioorg Med Chem Lett. 2021 May 15;40:127909. doi: 10.1016/j.bmcl.2021.127909. Epub 2021 Mar 9. Bioorg Med Chem Lett. 2021. PMID: 33705900

9

Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.

Liu W, Liu X, Tian L, Gao Y, Liu W, Chen H, Jiang X, Xu Z, Ding H, Zhao Q. Liu W, et al. Among authors: liu x. Eur J Med Chem. 2021 Oct 15;222:113554. doi: 10.1016/j.ejmech.2021.113554. Epub 2021 May 29. Eur J Med Chem. 2021. PMID: 34098466

10

Study on the experimental verification and regulatory mechanism of Rougui-Ganjiang herb-pair for the actions of thermogenesis in brown adipose tissue based on network pharmacology.

Liu X, Gao YP, Shen ZX, Qu YY, Liu WW, Yao D, Xing B, Xu ZH, Li X, Zhao QC. Liu X, et al. Among authors: liu ww. J Ethnopharmacol. 2021 Oct 28;279:114378. doi: 10.1016/j.jep.2021.114378. Epub 2021 Jun 27. J Ethnopharmacol. 2021. PMID: 34192599

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