Kulke D - Search Results

1

Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release.

Harrington S, Knox JJ, Burns AR, Choo KL, Au A, Kitner M, Haeberli C, Pyche J, D'Amata C, Kim YH, Volpatti JR, Guiliani M, Snider J, Wong V, Palmeira BM, Redman EM, Vaidya AS, Gilleard JS, Stagljar I, Cutler SR, Kulke D, Dowling JJ, Yip CM, Keiser J, Zasada I, Lautens M, Roy PJ. Harrington S, et al. Among authors: kulke d. Commun Biol. 2022 Aug 24;5(1):865. doi: 10.1038/s42003-022-03819-6. Commun Biol. 2022. PMID: 36002479 Free PMC article.

2

Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside.

Kulke D, von Samson-Himmelstjerna G, Miltsch SM, Wolstenholme AJ, Jex AR, Gasser RB, Ballesteros C, Geary TG, Keiser J, Townson S, Harder A, Krücken J. Kulke D, et al. PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3401. doi: 10.1371/journal.pntd.0003401. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25521608 Free PMC article.

3

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

Krücken J, Holden-Dye L, Keiser J, Prichard RK, Townson S, Makepeace BL, Hübner MP, Hahnel SR, Scandale I, Harder A, Kulke D. Krücken J, et al. Among authors: kulke d. PLoS Pathog. 2021 Jul 22;17(7):e1009682. doi: 10.1371/journal.ppat.1009682. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34293063 Free PMC article. Review.

4

Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential.

Harrington S, Pyche J, Burns AR, Spalholz T, Ryan KT, Baker RJ, Ching J, Rufener L, Lautens M, Kulke D, Vernudachi A, Zamanian M, Deuther-Conrad W, Brust P, Roy PJ. Harrington S, et al. Among authors: kulke d. Nat Commun. 2023 Mar 31;14(1):1816. doi: 10.1038/s41467-023-37452-6. Nat Commun. 2023. PMID: 37002199 Free PMC article.

5

Caenorhabditis elegans in anthelmintic research - Old model, new perspectives.

Hahnel SR, Dilks CM, Heisler I, Andersen EC, Kulke D. Hahnel SR, et al. Among authors: kulke d. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:237-248. doi: 10.1016/j.ijpddr.2020.09.005. Epub 2020 Oct 2. Int J Parasitol Drugs Drug Resist. 2020. PMID: 33249235 Free PMC article. Review.

6

Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans.

Hahnel SR, Roberts WM, Heisler I, Kulke D, Weeks JC. Hahnel SR, et al. Among authors: kulke d. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:174-187. doi: 10.1016/j.ijpddr.2021.05.005. Epub 2021 Jul 2. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34252686 Free PMC article.

7

In vivo efficacy of the anthelmintic tribendimidine against the cestode Hymenolepis microstoma in a controlled laboratory trial.

Kulke D, Krücken J, Welz C, von Samson-Himmelstjerna G, Harder A. Kulke D, et al. Acta Trop. 2012 Aug;123(2):78-84. doi: 10.1016/j.actatropica.2012.03.008. Epub 2012 Apr 1. Acta Trop. 2012. PMID: 22487754

8

In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis.

Kulke D, Krücken J, Demeler J, Harder A, Mehlhorn H, von Samson-Himmelstjerna G. Kulke D, et al. Parasitol Res. 2013 Jan;112(1):335-45. doi: 10.1007/s00436-012-3141-1. Epub 2012 Oct 2. Parasitol Res. 2013. PMID: 23052772

9

In vivo efficacy of PF1022A and nicotinic acetylcholine receptor agonists alone and in combination against Nippostrongylus brasiliensis.

Kulke D, Krücken J, Harder A, Krebber R, Fraatz K, Mehlhorn H, VON Samson-Himmelstjerna G. Kulke D, et al. Parasitology. 2013 Sep;140(10):1252-65. doi: 10.1017/S0031182013000632. Epub 2013 Jun 7. Parasitology. 2013. PMID: 23742764

10

Efficacy of cyclooctadepsipeptides and aminophenylamidines against larval, immature and mature adult stages of a parasitologically characterized trichurosis model in mice.

Kulke D, Krücken J, Harder A, von Samson-Himmelstjerna G. Kulke D, et al. PLoS Negl Trop Dis. 2014 Feb 20;8(2):e2698. doi: 10.1371/journal.pntd.0002698. eCollection 2014 Feb. PLoS Negl Trop Dis. 2014. PMID: 24587460 Free PMC article.

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