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Squalene in oil-based adjuvant improves the immunogenicity of SARS-CoV-2 RBD and confirms safety in animal models.
Choque-Guevara R, Poma-Acevedo A, Montesinos-Millán R, Rios-Matos D, Gutiérrez-Manchay K, Montalvan-Avalos A, Quiñones-Garcia S, Cauti-Mendoza MG, Agurto-Arteaga A, Ramirez-Ortiz I, Criollo-Orozco M, Huaccachi-Gonzales E, Romero YK, Perez-Martinez N, Isasi-Rivas G, Sernaque-Aguilar Y, Villanueva-Pérez D, Ygnacio F, Vallejos-Sánchez K, Fernández-Sánchez M, Guevara-Sarmiento LA, Fernández-Díaz M, Zimic M; COVID-19 Working Group in Perú. Choque-Guevara R, et al. Among authors: gutierrez manchay k. PLoS One. 2022 Aug 23;17(8):e0269823. doi: 10.1371/journal.pone.0269823. eCollection 2022. PLoS One. 2022. PMID: 35998134 Free PMC article.
Preclinical Assessment of IgY Antibodies Against Recombinant SARS-CoV-2 RBD Protein for Prophylaxis and Post-Infection Treatment of COVID-19.
Agurto-Arteaga A, Poma-Acevedo A, Rios-Matos D, Choque-Guevara R, Montesinos-Millán R, Montalván Á, Isasi-Rivas G, Cauna-Orocollo Y, Cauti-Mendoza MG, Pérez-Martínez N, Gutierrez-Manchay K, Ramirez-Ortiz I, Núñez-Fernández D, Salguedo-Bohorquez MI, Quiñones-Garcia S, Fernández Díaz M, Guevara Sarmiento LA, Zimic M; COVID-19 Working Group in Perú. Agurto-Arteaga A, et al. Among authors: gutierrez manchay k. Front Immunol. 2022 May 10;13:881604. doi: 10.3389/fimmu.2022.881604. eCollection 2022. Front Immunol. 2022. PMID: 35664008 Free PMC article.
Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 disease.
Díaz MF, Calderón K, Rojas-Neyra A, Vakharia VN, Choque-Guevara R, Montalvan-Avalos A, Poma-Acevedo A, Rios-Matos D, Agurto-Arteaga A, Cauti-Mendoza MG, Perez-Martinez N, Isasi-Rivas G, Tataje-Lavanda L, Sernaque-Aguilar Y, Ygnacio F, Criollo-Orozco M, Huaccachi-Gonzalez E, Delgado-Ccancce E, Villanueva-Pérez D, Montesinos-Millán R, Gutiérrez-Manchay K, Pauyac-Antezana K, Ramirez-Ortiz I, Quiñones-Garcia S, Cauna-Orocollo Y, Vallejos-Sánchez K, Rios-Angulo A, Núñez-Fernández D, Salguedo-Bohorquez MI, Ticona J, Fernández-Sánchez M, Icochea E, Guevara-Sarmiento LA, Zimic M; COVID-19 Working Group in Perú. Díaz MF, et al. Among authors: gutierrez manchay k. Sci Rep. 2022 Jun 20;12(1):10359. doi: 10.1038/s41598-022-13560-z. Sci Rep. 2022. PMID: 35725862 Free PMC article.