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Preferential Synaptic Type of GABA-A Receptor Ligands Enhancing Neuronal Survival and Facilitating Functional Recovery After Ischemic Stroke.
Mordyl B, Fajkis-Zajączkowska N, Szafrańska K, Siwek A, Głuch-Lutwin M, Żmudzki P, Jończyk J, Karcz T, Słoczyńska K, Pękala E, Pomierny B, Krzyżanowska W, Jurczyk J, Skórkowska A, Sałach A, Jastrzębska-Więsek M, Walczak M, Gawlik MT, Smolik M, Kolaczkowski M, Marcinkowska M. Mordyl B, et al. Among authors: jonczyk j. J Med Chem. 2024 Dec 26;67(24):21859-21889. doi: 10.1021/acs.jmedchem.4c01578. Epub 2024 Dec 12. J Med Chem. 2024. PMID: 39668673
Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.
Panek D, Pasieka A, Jończyk J, Gawlińska M, Zaręba P, Siwek A, Wolak M, Mordyl B, Głuch-Lutwin M, Latacz G, Brazzolotto X, Chantegreil F, Nachon F, Zdarova Karasova J, Pejchal J, Mzik M, Sestak V, Prchal L, Odvarkova J, Soukup O, Korabecny J, Sorf A, Hamsikova M, Zemanova L, Muckova L, Vánova N, Dryja P, Sałat K, Höfner G, Wanner K, Więckowska A, Malawska B. Panek D, et al. Among authors: jonczyk j. Angew Chem Int Ed Engl. 2024 Nov 11:e202420510. doi: 10.1002/anie.202420510. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39523866
2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators.
Marcinkowska M, Fajkis-Zajączkowska N, Szafrańska K, Jończyk J, Siwek A, Mordyl B, Karcz T, Latacz G, Kolaczkowski M. Marcinkowska M, et al. Among authors: jonczyk j. ACS Chem Neurosci. 2023 Mar 15;14(6):1166-1180. doi: 10.1021/acschemneuro.2c00800. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848624 Free PMC article.
New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease.
Czarnecka K, Girek M, Kręcisz P, Skibiński R, Łątka K, Jończyk J, Bajda M, Szymczyk P, Galita G, Kabziński J, Majsterek I, Espargaró A, Sabate R, Szymański P. Czarnecka K, et al. Among authors: jonczyk j. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2158822. doi: 10.1080/14756366.2022.2158822. J Enzyme Inhib Med Chem. 2023. PMID: 36629422 Free PMC article.
51 results