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hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia.
Pal D, Blair H, Parker J, Hockney S, Beckett M, Singh M, Tirtakusuma R, Nelson R, McNeill H, Angel SH, Wilson A, Nizami S, Nakjang S, Zhou P, Schwab C, Sinclair P, Russell LJ, Coxhead J, Halsey C, Allan JM, Harrison CJ, Moorman AV, Heidenreich O, Vormoor J. Pal D, et al. Among authors: singh m. Cell Rep Med. 2022 Aug 16;3(8):100717. doi: 10.1016/j.xcrm.2022.100717. Cell Rep Med. 2022. PMID: 35977468 Free PMC article.
MYC-dependent upregulation of the de novo serine and glycine synthesis pathway is a targetable metabolic vulnerability in group 3 medulloblastoma.
Adiamah M, Poole B, Lindsey JC, Kohe S, Morcavallo A, Burté F, Hill RM, Blair H, Thompson D, Singh M, Swartz S, Crosier S, Zhang T, Maddocks ODK, Peet A, Chesler L, Hickson I, Maxwell RJ, Clifford SC. Adiamah M, et al. Among authors: singh m. Neuro Oncol. 2025 Jan 12;27(1):237-253. doi: 10.1093/neuonc/noae179. Neuro Oncol. 2025. PMID: 39377369 Free PMC article.
Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy: A Randomized Clinical Trial With Open-Label Extension.
Adams D, Wixner J, Polydefkis M, Berk JL, Conceição IM, Dispenzieri A, Peltier A, Ueda M, Bender S, Capocelli K, Jay PY, Yureneva E, Obici L; patisiran Global OLE study group. Adams D, et al. JAMA Neurol. 2025 Jan 13. doi: 10.1001/jamaneurol.2024.4631. Online ahead of print. JAMA Neurol. 2025. PMID: 39804640
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