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Page 1
Drug-microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL.
Bruch PM, Giles HA, Kolb C, Herbst SA, Becirovic T, Roider T, Lu J, Scheinost S, Wagner L, Huellein J, Berest I, Kriegsmann M, Kriegsmann K, Zgorzelski C, Dreger P, Zaugg JB, Müller-Tidow C, Zenz T, Huber W, Dietrich S. Bruch PM, et al. Among authors: huellein j. Mol Syst Biol. 2022 Aug;18(8):e10855. doi: 10.15252/msb.202110855. Mol Syst Biol. 2022. PMID: 35959629 Free PMC article.
Survey of ex vivo drug combination effects in chronic lymphocytic leukemia reveals synergistic drug effects and genetic dependencies.
Lukas M, Velten B, Sellner L, Tomska K, Hüellein J, Walther T, Wagner L, Muley C, Wu B, Oleś M, Dietrich S, Jethwa A, Bohnenberger H, Lu J, Huber W, Zenz T. Lukas M, et al. Among authors: huellein j. Leukemia. 2020 Nov;34(11):2934-2950. doi: 10.1038/s41375-020-0846-5. Epub 2020 May 13. Leukemia. 2020. PMID: 32404973 Free PMC article.
Targeting the BRAF V600E mutation in multiple myeloma.
Andrulis M, Lehners N, Capper D, Penzel R, Heining C, Huellein J, Zenz T, von Deimling A, Schirmacher P, Ho AD, Goldschmidt H, Neben K, Raab MS. Andrulis M, et al. Among authors: huellein j. Cancer Discov. 2013 Aug;3(8):862-9. doi: 10.1158/2159-8290.CD-13-0014. Epub 2013 Apr 23. Cancer Discov. 2013. PMID: 23612012
TP53 mutation and survival in aggressive B cell lymphoma.
Zenz T, Kreuz M, Fuge M, Klapper W, Horn H, Staiger AM, Winter D, Helfrich H, Huellein J, Hansmann ML, Stein H, Feller A, Möller P, Schmitz N, Trümper L, Loeffler M, Siebert R, Rosenwald A, Ott G, Pfreundschuh M, Stilgenbauer S; German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL). Zenz T, et al. Among authors: huellein j. Int J Cancer. 2017 Oct 1;141(7):1381-1388. doi: 10.1002/ijc.30838. Epub 2017 Jun 26. Int J Cancer. 2017. PMID: 28614910 Clinical Trial.