Deng Z - Search Results

1

Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains.

Lu L, Zhai X, Li X, Wang S, Zhang L, Wang L, Jin X, Liang L, Deng Z, Li Z, Wang Y, Fu X, Hu H, Wang J, Mei Z, He Z, Wang F. Lu L, et al. Among authors: deng z. Nat Commun. 2022 Aug 9;13(1):4672. doi: 10.1038/s41467-022-32364-3. Nat Commun. 2022. PMID: 35945250 Free PMC article.

2

H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.

Ai H, Sun M, Liu A, Sun Z, Liu T, Cao L, Liang L, Qu Q, Li Z, Deng Z, Tong Z, Chu G, Tian X, Deng H, Zhao S, Li JB, Lou Z, Liu L. Ai H, et al. Among authors: deng z, deng h. Nat Chem Biol. 2022 Sep;18(9):972-980. doi: 10.1038/s41589-022-01067-7. Epub 2022 Jun 23. Nat Chem Biol. 2022. PMID: 35739357

3

Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.

Tong Z, Ai H, Xu Z, He K, Chu GC, Shi Q, Deng Z, Xue Q, Sun M, Du Y, Liang L, Li JB, Pan M, Liu L. Tong Z, et al. Among authors: deng z. Nat Struct Mol Biol. 2024 Feb;31(2):300-310. doi: 10.1038/s41594-023-01141-1. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177667

4

Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168.

Ai H, Tong Z, Deng Z, Shi Q, Tao S, Sun G, Liang J, Sun M, Wu X, Zheng Q, Liang L, Yin H, Li JB, Gao S, Tian C, Liu L, Pan M. Ai H, et al. Among authors: deng z. Nat Chem Biol. 2024 Oct 11. doi: 10.1038/s41589-024-01750-x. Online ahead of print. Nat Chem Biol. 2024. PMID: 39394267

5

RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA.

Zhang L, Deng Z, Du Y, Xu Z, Zhang T, Tong Z, Ai H, Liang LJ, Liu L. Zhang L, et al. Among authors: deng z. Bioorg Med Chem. 2025 Jan 1;117:118016. doi: 10.1016/j.bmc.2024.118016. Epub 2024 Nov 20. Bioorg Med Chem. 2025. PMID: 39580855

6

The Bre1/Rad6 machinery: writing the central histone ubiquitin mark on H2B and beyond.

Deng ZH, Ai HS, Lu CP, Li JB. Deng ZH, et al. Chromosome Res. 2020 Dec;28(3-4):247-258. doi: 10.1007/s10577-020-09640-3. Epub 2020 Sep 7. Chromosome Res. 2020. PMID: 32895784 Review.

7

Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.

Ai H, Chu GC, Gong Q, Tong ZB, Deng Z, Liu X, Yang F, Xu Z, Li JB, Tian C, Liu L. Ai H, et al. Among authors: deng z. J Am Chem Soc. 2022 Oct 12;144(40):18329-18337. doi: 10.1021/jacs.2c06156. Epub 2022 Sep 27. J Am Chem Soc. 2022. PMID: 36166692

8

Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16.

Ai H, He Z, Deng Z, Chu GC, Shi Q, Tong Z, Li JB, Pan M, Liu L. Ai H, et al. Among authors: deng z. Nat Struct Mol Biol. 2024 Nov;31(11):1745-1755. doi: 10.1038/s41594-024-01342-2. Epub 2024 Jun 25. Nat Struct Mol Biol. 2024. PMID: 38918638

9

Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair.

Feng LL, Bie SY, Deng ZH, Bai SM, Shi J, Qin CL, Liu HL, Li JX, Chen WY, Zhou JY, Jiao CM, Ma Y, Qiu MB, Ai HS, Zheng J, Hung MC, Wang YL, Wan XB, Fan XJ. Feng LL, et al. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2322972121. doi: 10.1073/pnas.2322972121. Epub 2024 Jul 5. Proc Natl Acad Sci U S A. 2024. PMID: 38968116

10

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.

Deng Z, Ai H, Sun M, Tong Z, Du Y, Qu Q, Zhang L, Xu Z, Tao S, Shi Q, Li JB, Pan M, Liu L. Deng Z, et al. Mol Cell. 2023 Sep 7;83(17):3080-3094.e14. doi: 10.1016/j.molcel.2023.08.001. Epub 2023 Aug 25. Mol Cell. 2023. PMID: 37633270 Free article.

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