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Mechanism of tandem duplication formation in BRCA1-mutant cells.
Willis NA, Frock RL, Menghi F, Duffey EE, Panday A, Camacho V, Hasty EP, Liu ET, Alt FW, Scully R. Willis NA, et al. Among authors: panday a. Nature. 2017 Nov 30;551(7682):590-595. doi: 10.1038/nature24477. Epub 2017 Nov 22. Nature. 2017. PMID: 29168504 Free PMC article.
Recombination and restart at blocked replication forks.
Scully R, Elango R, Panday A, Willis NA. Scully R, et al. Among authors: panday a. Curr Opin Genet Dev. 2021 Dec;71:154-162. doi: 10.1016/j.gde.2021.08.003. Epub 2021 Aug 28. Curr Opin Genet Dev. 2021. PMID: 34464818 Free PMC article. Review.
Exploiting CRISPR/Cas9 to engineer precise segmental deletions in mouse embryonic stem cells.
Elango R, Panday A, Willis NA, Scully R. Elango R, et al. Among authors: panday a. STAR Protoc. 2022 Aug 19;3(3):101551. doi: 10.1016/j.xpro.2022.101551. eCollection 2022 Sep 16. STAR Protoc. 2022. PMID: 36042887 Free PMC article.
In this protocol, we use CRISPR/Cas9 to generate large deletions of the entire coding region of a gene of interest, generating a hemizygous cell line. Next, we systematically engineer precise in-frame deletions within the intact wild-type allele, facilitating study …
In this protocol, we use CRISPR/Cas9 to generate large deletions of the entire coding region of a gene of interest, generating a …
67 results