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Autoantibody mimicry of hormone action at the thyrotropin receptor.
Faust B, Billesbølle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A. Faust B, et al. Among authors: saghatelian a. Nature. 2022 Sep;609(7928):846-853. doi: 10.1038/s41586-022-05159-1. Epub 2022 Aug 8. Nature. 2022. PMID: 35940205 Free PMC article.
Primate-specific ORF0 contributes to retrotransposon-mediated diversity.
Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. Denli AM, et al. Among authors: saghatelian a. Cell. 2015 Oct 22;163(3):583-93. doi: 10.1016/j.cell.2015.09.025. Epub 2015 Oct 22. Cell. 2015. PMID: 26496605 Free article.
HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective.
Chu Q, Diedrich JK, Vaughan JM, Donaldson CJ, Nunn MF, Lee KF, Saghatelian A. Chu Q, et al. Among authors: saghatelian a. J Am Chem Soc. 2016 Aug 3;138(30):9473-8. doi: 10.1021/jacs.6b03463. Epub 2016 Jul 19. J Am Chem Soc. 2016. PMID: 27379525 Free PMC article.
Identification of Microprotein-Protein Interactions via APEX Tagging.
Chu Q, Rathore A, Diedrich JK, Donaldson CJ, Yates JR 3rd, Saghatelian A. Chu Q, et al. Among authors: saghatelian a. Biochemistry. 2017 Jul 5;56(26):3299-3306. doi: 10.1021/acs.biochem.7b00265. Epub 2017 Jun 7. Biochemistry. 2017. PMID: 28589727 Free PMC article.
MIEF1 Microprotein Regulates Mitochondrial Translation.
Rathore A, Chu Q, Tan D, Martinez TF, Donaldson CJ, Diedrich JK, Yates JR 3rd, Saghatelian A. Rathore A, et al. Among authors: saghatelian a. Biochemistry. 2018 Sep 25;57(38):5564-5575. doi: 10.1021/acs.biochem.8b00726. Epub 2018 Sep 14. Biochemistry. 2018. PMID: 30215512 Free PMC article.
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Garcia D, et al. Among authors: saghatelian a. Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036. Cell Rep. 2019. PMID: 30605676 Free PMC article.
Regulation of the ER stress response by a mitochondrial microprotein.
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Chu Q, et al. Among authors: saghatelian a. Nat Commun. 2019 Oct 25;10(1):4883. doi: 10.1038/s41467-019-12816-z. Nat Commun. 2019. PMID: 31653868 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: saghatelian a. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis.
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, Leman LJ, Ghadiri MR. Chen PB, et al. Among authors: saghatelian a. Nat Biotechnol. 2020 Nov;38(11):1288-1297. doi: 10.1038/s41587-020-0549-5. Epub 2020 Jun 15. Nat Biotechnol. 2020. PMID: 32541956 Free PMC article.
170 results