Hu J - Search Results

1

A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to β-Lapachone for Cancer-Specific Targeting.

Gong Q, Li X, Li T, Wu X, Hu J, Yang F, Zhang X. Gong Q, et al. Among authors: hu j. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202210001. doi: 10.1002/anie.202210001. Epub 2022 Aug 23. Angew Chem Int Ed Engl. 2022. PMID: 35938884

2

A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials.

Gong Q, Hu J, Wang P, Li X, Zhang X. Gong Q, et al. Among authors: hu j. Eur J Med Chem. 2021 Jan 15;210:112962. doi: 10.1016/j.ejmech.2020.112962. Epub 2020 Oct 22. Eur J Med Chem. 2021. PMID: 33158575 Review.

3

Reactive Oxygen Species (ROS)-Responsive Prodrugs, Probes, and Theranostic Prodrugs: Applications in the ROS-Related Diseases.

Wang P, Gong Q, Hu J, Li X, Zhang X. Wang P, et al. Among authors: hu j. J Med Chem. 2021 Jan 14;64(1):298-325. doi: 10.1021/acs.jmedchem.0c01704. Epub 2020 Dec 23. J Med Chem. 2021. PMID: 33356214 Review.

4

Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1.

Gong Q, Yu Q, Wang N, Hu J, Wang P, Yang F, Li T, You Q, Li X, Zhang X. Gong Q, et al. Among authors: hu j. Eur J Med Chem. 2021 Oct 5;221:113515. doi: 10.1016/j.ejmech.2021.113515. Epub 2021 May 6. Eur J Med Chem. 2021. PMID: 33984806

5

Rational designed highly sensitive NQO1-activated near-infrared fluorescent probe combined with NQO1 substrates in vivo: An innovative strategy for NQO1-overexpressing cancer theranostics.

Gong Q, Yang F, Hu J, Li T, Wang P, Li X, Zhang X. Gong Q, et al. Among authors: hu j. Eur J Med Chem. 2021 Nov 15;224:113707. doi: 10.1016/j.ejmech.2021.113707. Epub 2021 Jul 19. Eur J Med Chem. 2021. PMID: 34303080

6

Novel NQO1 substrates bearing two nitrogen redox centers: Design, synthesis, molecular dynamics simulations, and antitumor evaluation.

Gong Q, Wang P, Li T, Yu Z, Yang L, Wu C, Hu J, Yang F, Zhang X, Li X. Gong Q, et al. Among authors: hu j. Bioorg Chem. 2023 May;134:106480. doi: 10.1016/j.bioorg.2023.106480. Epub 2023 Mar 15. Bioorg Chem. 2023. PMID: 36958178

7

Shikonin N-benzyl matrinic acid ester derivatives as novel telomerase inhibitors with potent activity against lung cancer cell lines.

Han H, He C, Chen X, Luo Y, Yang M, Wen Z, Hu J, Lin F, Han M, Yin T, Yang R, Lin H, Qi J, Yang Y. Han H, et al. Among authors: hu j. Bioorg Med Chem Lett. 2022 Feb 1;57:128503. doi: 10.1016/j.bmcl.2021.128503. Epub 2021 Dec 15. Bioorg Med Chem Lett. 2022. PMID: 34922028

8

Identification of novel topoisomerase II alpha inhibitors by virtual screening, molecular docking, and bioassay.

Yu C, Hu J, Luyten W, Sun D, Jiang T. Yu C, et al. Among authors: hu j. Chem Biol Drug Des. 2022 Jan;99(1):92-102. doi: 10.1111/cbdd.13927. Epub 2021 Aug 15. Chem Biol Drug Des. 2022. PMID: 34310071

9

A Multichannel Fluorescent Tongue for Amyloid-β Aggregates Detection.

Li F, Zhou L, Gao X, Ni W, Hu J, Wu M, Chen S, Han J, Wu J. Li F, et al. Among authors: hu j. Int J Mol Sci. 2022 Nov 23;23(23):14562. doi: 10.3390/ijms232314562. Int J Mol Sci. 2022. PMID: 36498895 Free PMC article.

10

Machine learning-assisted pattern recognition and imaging of multiplexed cancer cells via a porphyrin-embedded dendrimer array.

Hu J, Ni W, Han M, Zhan Y, Li F, Huang H, Han J. Hu J, et al. J Mater Chem B. 2024 Dec 18;13(1):207-217. doi: 10.1039/d4tb01861c. J Mater Chem B. 2024. PMID: 39545798

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