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Page 1
The loss of pancreatic islet NADPH oxidase (NOX)2 improves islet transplantation.
Wrublewsky S, Glas J, Carlein C, Nalbach L, Hoffmann MDA, Pack M, Vilas-Boas EA, Ribot N, Kappl R, Menger MD, Laschke MW, Ampofo E, Roma LP. Wrublewsky S, et al. Among authors: hoffmann mda. Redox Biol. 2022 Sep;55:102419. doi: 10.1016/j.redox.2022.102419. Epub 2022 Jul 31. Redox Biol. 2022. PMID: 35933903 Free PMC article.
Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells.
Nunes Marsiglio-Librais G, Aparecida Vilas-Boas E, Carlein C, Hoffmann MDA, Roma LP, Carpinelli AR. Nunes Marsiglio-Librais G, et al. Among authors: hoffmann mda. Redox Rep. 2020 Dec;25(1):41-50. doi: 10.1080/13510002.2020.1757877. Redox Rep. 2020. PMID: 32354273 Free PMC article.
A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes.
Scherschel M, Niemeier JO, Jacobs LJHC, Hoffmann MDA, Diederich A, Bell C, Höhne P, Raetz S, Kroll JB, Steinbeck J, Lichtenauer S, Multhoff J, Zimmermann J, Sadhanasatish T, Rothemann RA, Grashoff C, Messens J, Ampofo E, Laschke MW, Riemer J, Roma LP, Schwarzländer M, Morgan B. Scherschel M, et al. Among authors: hoffmann mda. Nat Commun. 2024 Dec 19;15(1):10704. doi: 10.1038/s41467-024-55302-x. Nat Commun. 2024. PMID: 39702652 Free PMC article.
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
Lorza-Gil E, Kaiser G, Carlein C, Hoffmann MDA, König GM, Haug S, Prates Roma L, Rexen Ulven E, Ulven T, Kostenis E, Birkenfeld AL, Häring HU, Ullrich S, Gerst F. Lorza-Gil E, et al. Among authors: hoffmann mda. Diabetologia. 2023 Aug;66(8):1501-1515. doi: 10.1007/s00125-023-05932-5. Epub 2023 May 23. Diabetologia. 2023. PMID: 37217659 Free PMC article.
Targeting Pancreatic Islet NLRP3 Improves Islet Graft Revascularization.
Wrublewsky S, Speer T, Nalbach L, Boewe AS, Pack M, Alansary D, Roma LP, Hoffmann MDA, Schmitt BM, Weinzierl A, Menger MD, Laschke MW, Ampofo E. Wrublewsky S, et al. Among authors: hoffmann mda. Diabetes. 2022 Aug 1;71(8):1706-1720. doi: 10.2337/db21-0851. Diabetes. 2022. PMID: 35622000