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S-nitrosylation is required for β2AR desensitization and experimental asthma.
Fonseca FV, Raffay TM, Xiao K, McLaughlin PJ, Qian Z, Grimmett ZW, Adachi N, Wang B, Hausladen A, Cobb BA, Zhang R, Hess DT, Gaston B, Lambert NA, Reynolds JD, Premont RT, Stamler JS. Fonseca FV, et al. Among authors: xiao k. Mol Cell. 2022 Aug 18;82(16):3089-3102.e7. doi: 10.1016/j.molcel.2022.06.033. Epub 2022 Aug 4. Mol Cell. 2022. PMID: 35931084 Free PMC article.
Recent developments in biased agonism.
Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Wisler JW, et al. Among authors: xiao k. Curr Opin Cell Biol. 2014 Apr;27:18-24. doi: 10.1016/j.ceb.2013.10.008. Epub 2013 Nov 20. Curr Opin Cell Biol. 2014. PMID: 24680426 Free PMC article. Review.
Beta-arrestin-mediated localization of smoothened to the primary cilium.
Kovacs JJ, Whalen EJ, Liu R, Xiao K, Kim J, Chen M, Wang J, Chen W, Lefkowitz RJ. Kovacs JJ, et al. Among authors: xiao k. Science. 2008 Jun 27;320(5884):1777-81. doi: 10.1126/science.1157983. Epub 2008 May 22. Science. 2008. PMID: 18497258 Free PMC article.
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.
Shenoy SK, Modi AS, Shukla AK, Xiao K, Berthouze M, Ahn S, Wilkinson KD, Miller WE, Lefkowitz RJ. Shenoy SK, et al. Among authors: xiao k. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6650-5. doi: 10.1073/pnas.0901083106. Epub 2009 Apr 10. Proc Natl Acad Sci U S A. 2009. PMID: 19363159 Free PMC article.
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, Mizuno K, Ma'ayan A, Gygi SP, Lefkowitz RJ. Xiao K, et al. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15299-304. doi: 10.1073/pnas.1008461107. Epub 2010 Aug 4. Proc Natl Acad Sci U S A. 2010. PMID: 20686112 Free PMC article.
2,357 results