Xu Y - Search Results

1

Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.

Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X. Zhuang H, et al. Among authors: xu g, xu y. J Biol Chem. 2022 Sep;298(9):102314. doi: 10.1016/j.jbc.2022.102314. Epub 2022 Aug 1. J Biol Chem. 2022. PMID: 35926709 Free PMC article.

2

A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway.

Zhang Z, Mao H, Du X, Zhu J, Xu Y, Wang S, Xu X, Ji P, Yu Y, Cao B, Han K, Hou T, Xu Z, Kong Y, Jiang G, Tang X, Qiao C, Mao X. Zhang Z, et al. Among authors: xu x, xu y, xu z. Oncotarget. 2016 Feb 23;7(8):9296-308. doi: 10.18632/oncotarget.6974. Oncotarget. 2016. PMID: 26814430 Free PMC article.

3

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway.

Zhang Z, Mao H, Du X, Zhu J, Xu Y, Wang S, Xu X, Ji P, Yu Y, Cao B, Han K, Hou T, Xu Z, Kong Y, Jiang G, Tang X, Qiao C, Mao X. Zhang Z, et al. Among authors: xu x, xu y, xu z. Oncotarget. 2016 Dec 6;7(49):81972. doi: 10.18632/oncotarget.13803. Oncotarget. 2016. PMID: 28082727 Free PMC article. No abstract available.

4

A novel STAT3 inhibitor negatively modulates platelet activation and aggregation.

Xu Z, Xu YJ, Hao YN, Ren LJ, Zhang ZB, Xu X, Cao BY, Dai KS, Zhu L, Fang Q, Kong Y, Mao XL. Xu Z, et al. Among authors: xu yj, xu x. Acta Pharmacol Sin. 2017 May;38(5):651-659. doi: 10.1038/aps.2016.155. Epub 2017 Mar 6. Acta Pharmacol Sin. 2017. PMID: 28260800 Free PMC article.

5

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis.

Xu Y, Zhang Z, Li J, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran MF, Zeng Y, Mao X. Xu Y, et al. J Hematol Oncol. 2017 Jul 3;10(1):132. doi: 10.1186/s13045-017-0499-7. J Hematol Oncol. 2017. PMID: 28673317 Free PMC article.

6

The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex.

Wang S, Li J, Du Y, Xu Y, Wang Y, Zhang Z, Xu Z, Zeng Y, Mao X, Cao B. Wang S, et al. Among authors: xu y, xu z. J Pharmacol Sci. 2017 Aug;134(4):197-202. doi: 10.1016/j.jphs.2017.07.001. Epub 2017 Jul 19. J Pharmacol Sci. 2017. PMID: 28779993 Free article.

7

Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.

Wang S, Juan J, Zhang Z, Du Y, Xu Y, Tong J, Cao B, Moran MF, Zeng Y, Mao X. Wang S, et al. Among authors: xu y. Cell Death Dis. 2017 Sep 21;8(9):e3058. doi: 10.1038/cddis.2017.450. Cell Death Dis. 2017. PMID: 28933784 Free PMC article.

8

The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor.

Du Y, Liu Y, Xu Y, Juan J, Zhang Z, Xu Z, Cao B, Wang Q, Zeng Y, Mao X. Du Y, et al. Among authors: xu y, xu z. J Biol Chem. 2018 Apr 20;293(16):5847-5859. doi: 10.1074/jbc.RA117.000972. Epub 2018 Feb 21. J Biol Chem. 2018. PMID: 29467225 Free PMC article.

9

Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.

Chen XH, Xu YJ, Wang XG, Lin P, Cao BY, Zeng YY, Wang Q, Zhang ZB, Mao XL, Zhang T. Chen XH, et al. Acta Pharmacol Sin. 2019 Dec;40(12):1568-1577. doi: 10.1038/s41401-019-0249-1. Epub 2019 Jun 13. Acta Pharmacol Sin. 2019. PMID: 31197245 Free PMC article.

10

RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.

Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL. Ren Y, et al. Among authors: xu yj, xu x. Acta Pharmacol Sin. 2020 Mar;41(3):394-403. doi: 10.1038/s41401-019-0309-6. Epub 2019 Oct 23. Acta Pharmacol Sin. 2020. PMID: 31645658 Free PMC article.

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