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miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Shopit A, Li X, Tang Z, Awsh M, Shobet L, Niu M, Wang H, Mousa H, Alshwmi M, Tesfaldet T, Gamallat Y, Li H, Chu P, Ahmad N, Jamalat Y, Ai J, Qaed E, Almoiliqy M, Wang S, Tang Z. Shopit A, et al. Among authors: wang h, wang s. Pharmacol Res. 2020 Nov;161:105130. doi: 10.1016/j.phrs.2020.105130. Epub 2020 Aug 17. Pharmacol Res. 2020. PMID: 32818653
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