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An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy.
MAbs. 2022 Jan-Dec;14(1):2088454. doi: 10.1080/19420862.2022.2088454.
MAbs. 2022.
PMID: 35924382
Free PMC article.
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
Lutz EA, Agarwal Y, Momin N, Cowles SC, Palmeri JR, Duong E, Hornet V, Sheen A, Lax BM, Rothschilds AM, Irvine DJ, Spranger S, Wittrup KD.
Lutz EA, et al. Among authors: cowles sc.
Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2205983119. doi: 10.1073/pnas.2205983119. Epub 2022 Aug 29.
Proc Natl Acad Sci U S A. 2022.
PMID: 36037341
Free PMC article.
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Tumor-localized catalases can fail to alter tumor growth and transcriptional profiles in subcutaneous syngeneic mouse tumor models.
Sheen A, Agarwal Y, Cheah KM, Cowles SC, Stinson JA, Palmeri JR, Sikes HD, Wittrup KD.
Sheen A, et al. Among authors: cowles sc.
Redox Biol. 2023 Aug;64:102766. doi: 10.1016/j.redox.2023.102766. Epub 2023 Jun 5.
Redox Biol. 2023.
PMID: 37311396
Free PMC article.
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Illuminating protein space with a programmable generative model.
Ingraham JB, Baranov M, Costello Z, Barber KW, Wang W, Ismail A, Frappier V, Lord DM, Ng-Thow-Hing C, Van Vlack ER, Tie S, Xue V, Cowles SC, Leung A, Rodrigues JV, Morales-Perez CL, Ayoub AM, Green R, Puentes K, Oplinger F, Panwar NV, Obermeyer F, Root AR, Beam AL, Poelwijk FJ, Grigoryan G.
Ingraham JB, et al. Among authors: cowles sc.
Nature. 2023 Nov;623(7989):1070-1078. doi: 10.1038/s41586-023-06728-8. Epub 2023 Nov 15.
Nature. 2023.
PMID: 37968394
Free PMC article.
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