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Placental DNA methylation profiles in opioid-exposed pregnancies and associations with the neonatal opioid withdrawal syndrome.
Radhakrishna U, Vishweswaraiah S, Uppala LV, Szymanska M, Macknis J, Kumar S, Saleem-Rasheed F, Aydas B, Forray A, Muvvala SB, Mishra NK, Guda C, Carey DJ, Metpally RP, Crist RC, Berrettini WH, Bahado-Singh RO. Radhakrishna U, et al. Among authors: uppala lv. Genomics. 2021 May;113(3):1127-1135. doi: 10.1016/j.ygeno.2021.03.006. Epub 2021 Mar 9. Genomics. 2021. PMID: 33711455 Free article.
Maternal opioid use disorder: Placental transcriptome analysis for neonatal opioid withdrawal syndrome.
Radhakrishna U, Nath SK, Vishweswaraiah S, Uppala LV, Forray A, Muvvala SB, Mishra NK, Southekal S, Guda C, Govindamangalam H, Vargas D, Gardella WG, Crist RC, Berrettini WH, Metpally RP, Bahado-Singh RO. Radhakrishna U, et al. Among authors: uppala lv. Genomics. 2021 Nov;113(6):3610-3617. doi: 10.1016/j.ygeno.2021.08.001. Epub 2021 Aug 3. Genomics. 2021. PMID: 34352367 Free article.
Cytochrome P450 Genes Mediated by DNA Methylation Are Involved in the Resistance to Hidradenitis Suppurativa.
Radhakrishna U, Ratnamala U, Jhala DD, Vadsaria N, Patel M, Uppala LV, Vedangi A, Saiyed N, Rawal RM, Damiani G, Jemec GBE. Radhakrishna U, et al. Among authors: uppala lv. J Invest Dermatol. 2023 Apr;143(4):670-673.e19. doi: 10.1016/j.jid.2022.08.056. Epub 2022 Sep 23. J Invest Dermatol. 2023. PMID: 36155054 Free article. No abstract available.
Hidradenitis suppurativa presents a methylome dysregulation capable to explain the pro-inflammatory microenvironment: Are these DNA methylations potential therapeutic targets?
Radhakrishna U, Ratnamala U, Jhala DD, Uppala LV, Vedangi A, Patel M, Vadsaria N, Shah S, Saiyed N, Rawal RM, Mercuri SR, Jemec GBE, Damiani G. Radhakrishna U, et al. Among authors: uppala lv. J Eur Acad Dermatol Venereol. 2023 Oct;37(10):2109-2123. doi: 10.1111/jdv.19286. Epub 2023 Jul 14. J Eur Acad Dermatol Venereol. 2023. PMID: 37338327
Placental microRNA methylome signatures may serve as biomarkers and therapeutic targets for prenatally opioid-exposed infants with neonatal opioid withdrawal syndrome.
Radhakrishna U, Nath SK, Uppala LV, Veerappa A, Forray A, Muvvala SB, Metpally RP, Crist RC, Berrettini WH, Mausi LM, Vishweswaraiah S, Bahado-Singh RO. Radhakrishna U, et al. Among authors: uppala lv. Front Genet. 2023 Jun 15;14:1215472. doi: 10.3389/fgene.2023.1215472. eCollection 2023. Front Genet. 2023. PMID: 37434949 Free PMC article.
Hidradenitis suppurativa associated telomere-methylome dysregulations in blood.
Radhakrishna U, Ratnamala U, Jhala DD, Uppala LV, Vedangi A, Saiyed N, Patel M, Vadsaria N, Shah SR, Rawal RM, Mercuri SR, McGonagle D, Jemec GBE, Damiani G. Radhakrishna U, et al. Among authors: uppala lv. J Eur Acad Dermatol Venereol. 2024 Feb;38(2):393-403. doi: 10.1111/jdv.19586. Epub 2023 Dec 6. J Eur Acad Dermatol Venereol. 2024. PMID: 37872100
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome.
Radhakrishna U, Radhakrishnan R, Uppala LV, Muvvala SB, Prajapati J, Rawal RM, Bahado-Singh RO, Sadhasivam S. Radhakrishna U, et al. Among authors: uppala lv. Front Neurosci. 2024 Aug 19;18:1442915. doi: 10.3389/fnins.2024.1442915. eCollection 2024. Front Neurosci. 2024. PMID: 39238930 Free PMC article.
DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa.
Radhakrishna U, Ratnamala U, Jhala DD, Uppala LV, Vedangi A, Saiyed N, Shah SR, Patel M, Rawal RM, Mazza T, Jemec GBE, Mazzoccoli G, Damiani G. Radhakrishna U, et al. Among authors: uppala lv. Front Immunol. 2024 Nov 26;15:1475424. doi: 10.3389/fimmu.2024.1475424. eCollection 2024. Front Immunol. 2024. PMID: 39669567 Free PMC article.
12 results