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Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.
Brussee JM, Vet NJ, Krekels EHJ, Valkenburg AJ, Jacqz-Aigrain E, van Gerven JMA, Swart EL, van den Anker JN, Tibboel D, de Hoog M, de Wildt SN, Knibbe CAJ. Brussee JM, et al. Among authors: krekels ehj. Br J Clin Pharmacol. 2018 Feb;84(2):358-368. doi: 10.1111/bcp.13459. Epub 2017 Nov 29. Br J Clin Pharmacol. 2018. PMID: 29072785 Free PMC article.
Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments.
Calvier EAM, Krekels EHJ, Yu H, Välitalo PAJ, Johnson TN, Rostami-Hodjegan A, Tibboel D, van der Graaf PH, Danhof M, Knibbe CAJ. Calvier EAM, et al. Among authors: krekels ehj. CPT Pharmacometrics Syst Pharmacol. 2018 Mar;7(3):175-185. doi: 10.1002/psp4.12273. Epub 2018 Feb 5. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29399979 Free PMC article.
97 results