Maynard JA - Search Results

1

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis.

DiVenere AM, Amengor D, Silva RP, Goldsmith JA, McLellan JS, Maynard JA. DiVenere AM, et al. Among authors: maynard ja. mBio. 2022 Aug 30;13(4):e0152722. doi: 10.1128/mbio.01527-22. Epub 2022 Aug 3. mBio. 2022. PMID: 35920558 Free PMC article.

2

Characterization of a key neutralizing epitope on pertussis toxin recognized by monoclonal antibody 1B7.

Sutherland JN, Maynard JA. Sutherland JN, et al. Among authors: maynard ja. Biochemistry. 2009 Dec 22;48(50):11982-93. doi: 10.1021/bi901532z. Biochemistry. 2009. PMID: 19899804 Free PMC article.

3

Antibodies recognizing protective pertussis toxin epitopes are preferentially elicited by natural infection versus acellular immunization.

Sutherland JN, Chang C, Yoder SM, Rock MT, Maynard JA. Sutherland JN, et al. Among authors: maynard ja. Clin Vaccine Immunol. 2011 Jun;18(6):954-62. doi: 10.1128/CVI.00561-10. Epub 2011 Apr 20. Clin Vaccine Immunol. 2011. PMID: 21508166 Free PMC article.

4

The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.

Wang X, Gray MC, Hewlett EL, Maynard JA. Wang X, et al. Among authors: maynard ja. J Biol Chem. 2015 Feb 6;290(6):3576-91. doi: 10.1074/jbc.M114.585281. Epub 2014 Dec 10. J Biol Chem. 2015. PMID: 25505186 Free PMC article.

5

A cocktail of humanized anti-pertussis toxin antibodies limits disease in murine and baboon models of whooping cough.

Nguyen AW, Wagner EK, Laber JR, Goodfield LL, Smallridge WE, Harvill ET, Papin JF, Wolf RF, Padlan EA, Bristol A, Kaleko M, Maynard JA. Nguyen AW, et al. Among authors: maynard ja. Sci Transl Med. 2015 Dec 2;7(316):316ra195. doi: 10.1126/scitranslmed.aad0966. Sci Transl Med. 2015. PMID: 26631634 Free PMC article.

6

Synergistic Neutralization of Pertussis Toxin by a Bispecific Antibody In Vitro and In Vivo.

Wagner EK, Wang X, Bui A, Maynard JA. Wagner EK, et al. Among authors: maynard ja. Clin Vaccine Immunol. 2016 Nov 4;23(11):851-862. doi: 10.1128/CVI.00371-16. Print 2016 Nov. Clin Vaccine Immunol. 2016. PMID: 27581436 Free PMC article.

7

Prior exposure to Bordetella species as an exclusion criterion in the baboon model of pertussis.

Nguyen AW, Wagner EK, Posada L, Liu X, Connelly S, Papin JF, Wolf RF, Kaleko M, Maynard JA. Nguyen AW, et al. Among authors: maynard ja. J Vet Med Sci. 2017 Jan 20;79(1):60-64. doi: 10.1292/jvms.16-0427. Epub 2016 Sep 26. J Vet Med Sci. 2017. PMID: 27666464 Free PMC article.

8

Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.

Wang X, Stapleton JA, Klesmith JR, Hewlett EL, Whitehead TA, Maynard JA. Wang X, et al. Among authors: maynard ja. Biochemistry. 2017 Mar 7;56(9):1324-1336. doi: 10.1021/acs.biochem.6b01163. Epub 2017 Feb 23. Biochemistry. 2017. PMID: 28177609 Free PMC article.

9

Charge Shielding Prevents Aggregation of Supercharged GFP Variants at High Protein Concentration.

Laber JR, Dear BJ, Martins ML, Jackson DE, DiVenere A, Gollihar JD, Ellington AD, Truskett TM, Johnston KP, Maynard JA. Laber JR, et al. Among authors: maynard ja. Mol Pharm. 2017 Oct 2;14(10):3269-3280. doi: 10.1021/acs.molpharmaceut.7b00322. Epub 2017 Sep 18. Mol Pharm. 2017. PMID: 28870080 Free PMC article.

10

Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization.

Acquaye-Seedah E, Reczek EE, Russell HH, DiVenere AM, Sandman SO, Collins JH, Stein CA, Whitehead TA, Maynard JA. Acquaye-Seedah E, et al. Among authors: maynard ja. Infect Immun. 2018 May 22;86(6):e00004-18. doi: 10.1128/IAI.00004-18. Print 2018 Jun. Infect Immun. 2018. PMID: 29581192 Free PMC article.

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