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Page 1
Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth.
Delle Donne R, Iannucci R, Rinaldi L, Roberto L, Oliva MA, Senatore E, Borzacchiello D, Lignitto L, Giurato G, Rizzo F, Sellitto A, Chiuso F, Castaldo S, Scala G, Campani V, Nele V, De Rosa G, D'Ambrosio C, Garbi C, Scaloni A, Weisz A, Ambrosino C, Arcella A, Feliciello A. Delle Donne R, et al. Commun Biol. 2022 Aug 2;5(1):780. doi: 10.1038/s42003-022-03639-8. Commun Biol. 2022. PMID: 35918402 Free PMC article.
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.
Lignitto L, Arcella A, Sepe M, Rinaldi L, Delle Donne R, Gallo A, Stefan E, Bachmann VA, Oliva MA, Tiziana Storlazzi C, L'Abbate A, Brunetti A, Gargiulo S, Gramanzini M, Insabato L, Garbi C, Gottesman ME, Feliciello A. Lignitto L, et al. Among authors: delle donne r. Nat Commun. 2013;4:1822. doi: 10.1038/ncomms2791. Nat Commun. 2013. PMID: 23652010 Free PMC article.
Proteolytic control of neurite outgrowth inhibitor NOGO-A by the cAMP/PKA pathway.
Sepe M, Lignitto L, Porpora M, Delle Donne R, Rinaldi L, Belgianni G, Colucci G, Cuomo O, Viggiano D, Scorziello A, Garbi C, Annunziato L, Feliciello A. Sepe M, et al. Among authors: delle donne r. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15729-34. doi: 10.1073/pnas.1410274111. Epub 2014 Oct 20. Proc Natl Acad Sci U S A. 2014. PMID: 25331889 Free PMC article.
praja2 regulates KSR1 stability and mitogenic signaling.
Rinaldi L, Delle Donne R, Sepe M, Porpora M, Garbi C, Chiuso F, Gallo A, Parisi S, Russo L, Bachmann V, Huber RG, Stefan E, Russo T, Feliciello A. Rinaldi L, et al. Among authors: delle donne r. Cell Death Dis. 2016 May 19;7(5):e2230. doi: 10.1038/cddis.2016.109. Cell Death Dis. 2016. PMID: 27195677 Free PMC article.
Mitochondrial AKAP1 supports mTOR pathway and tumor growth.
Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A. Rinaldi L, et al. Among authors: delle donne r. Cell Death Dis. 2017 Jun 1;8(6):e2842. doi: 10.1038/cddis.2017.241. Cell Death Dis. 2017. PMID: 28569781 Free PMC article.
Counterregulation of cAMP-directed kinase activities controls ciliogenesis.
Porpora M, Sauchella S, Rinaldi L, Delle Donne R, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann VA, Synofzik M, Lindner HH, Conte I, Stefan E, Feliciello A. Porpora M, et al. Among authors: delle donne r. Nat Commun. 2018 Mar 26;9(1):1224. doi: 10.1038/s41467-018-03643-9. Nat Commun. 2018. PMID: 29581457 Free PMC article.
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.
Rinaldi L, Delle Donne R, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A. Rinaldi L, et al. Among authors: delle donne r. Nat Commun. 2019 Jun 12;10(1):2572. doi: 10.1038/s41467-019-10037-y. Nat Commun. 2019. PMID: 31189917 Free PMC article.
The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation.
Senatore E, Chiuso F, Rinaldi L, Intartaglia D, Delle Donne R, Pedone E, Catalanotti B, Pirone L, Fiorillo B, Moraca F, Giamundo G, Scala G, Raffeiner A, Torres-Quesada O, Stefan E, Kwiatkowski M, van Pijkeren A, Morleo M, Franco B, Garbi C, Conte I, Feliciello A. Senatore E, et al. Among authors: delle donne r. EMBO J. 2021 May 17;40(10):e106503. doi: 10.15252/embj.2020106503. Epub 2021 May 2. EMBO J. 2021. PMID: 33934390 Free PMC article.
Pathophysiology of Primary Cilia: Signaling and Proteostasis Regulation.
Senatore E, Iannucci R, Chiuso F, Delle Donne R, Rinaldi L, Feliciello A. Senatore E, et al. Among authors: delle donne r. Front Cell Dev Biol. 2022 May 11;10:833086. doi: 10.3389/fcell.2022.833086. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35646931 Free PMC article. Review.
13 results