Dobbelstein M - Search Results

1

Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair.

Bolgi O, Silva-Garcia M, Ross B, Pilla E, Kari V, Killisch M, Spitzner M, Stark N, Lenz C, Weiss K, Donzelli L, Gorrell MD, Grade M, Riemer J, Urlaub H, Dobbelstein M, Huber R, Geiss-Friedlander R. Bolgi O, et al. Among authors: dobbelstein m. EMBO Rep. 2022 Oct 6;23(10):e54136. doi: 10.15252/embr.202154136. Epub 2022 Aug 1. EMBO Rep. 2022. PMID: 35912982 Free PMC article.

2

Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.

Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, Kitz J, Kaulfuß S, Beißbarth T, Dobbelstein M, Ghadimi M, Grade M, Gaedcke J. Salendo J, et al. Among authors: dobbelstein m. Radiother Oncol. 2013 Sep;108(3):451-7. doi: 10.1016/j.radonc.2013.06.032. Epub 2013 Aug 7. Radiother Oncol. 2013. PMID: 23932154

3

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness.

Kari V, Mansour WY, Raul SK, Baumgart SJ, Mund A, Grade M, Sirma H, Simon R, Will H, Dobbelstein M, Dikomey E, Johnsen SA. Kari V, et al. Among authors: dobbelstein m. EMBO Rep. 2016 Nov;17(11):1609-1623. doi: 10.15252/embr.201642352. Epub 2016 Sep 5. EMBO Rep. 2016. PMID: 27596623 Free PMC article.

4

Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. Kramer D, et al. Among authors: dobbelstein m. Cell Death Differ. 2017 Feb;24(2):300-316. doi: 10.1038/cdd.2016.124. Epub 2016 Nov 11. Cell Death Differ. 2017. PMID: 27834954 Free PMC article.

5

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness.

Kari V, Mansour WY, Raul SK, Baumgart SJ, Mund A, Grade M, Sirma H, Simon R, Will H, Dobbelstein M, Dikomey E, Johnsen SA. Kari V, et al. Among authors: dobbelstein m. EMBO Rep. 2018 Oct;19(10):e46783. doi: 10.15252/embr.201846783. EMBO Rep. 2018. PMID: 30291165 Free PMC article.

6

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.

Landmann H, Proia DA, He S, Ogawa LS, Kramer F, Beißbarth T, Grade M, Gaedcke J, Ghadimi M, Moll U, Dobbelstein M. Landmann H, et al. Among authors: dobbelstein m. Cell Death Dis. 2014 Sep 11;5(9):e1411. doi: 10.1038/cddis.2014.378. Cell Death Dis. 2014. PMID: 25210794 Free PMC article.

7

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion.

Schulz-Heddergott R, Stark N, Edmunds SJ, Li J, Conradi LC, Bohnenberger H, Ceteci F, Greten FR, Dobbelstein M, Moll UM. Schulz-Heddergott R, et al. Among authors: dobbelstein m. Cancer Cell. 2018 Aug 13;34(2):298-314.e7. doi: 10.1016/j.ccell.2018.07.004. Cancer Cell. 2018. PMID: 30107178 Free PMC article.

8

Correction: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. Kramer D, et al. Among authors: dobbelstein m. Cell Death Differ. 2019 Mar;26(4):780. doi: 10.1038/s41418-018-0190-8. Cell Death Differ. 2019. PMID: 30177736 Free PMC article.

9

Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity.

Köpper F, Bierwirth C, Schön M, Kunze M, Elvers I, Kranz D, Saini P, Menon MB, Walter D, Sørensen CS, Gaestel M, Helleday T, Schön MP, Dobbelstein M. Köpper F, et al. Among authors: dobbelstein m. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16856-61. doi: 10.1073/pnas.1304355110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082115 Free PMC article.

10

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.

Srinivas US, Dyczkowski J, Beißbarth T, Gaedcke J, Mansour WY, Borgmann K, Dobbelstein M. Srinivas US, et al. Among authors: dobbelstein m. Oncotarget. 2015 May 20;6(14):12574-86. doi: 10.18632/oncotarget.3728. Oncotarget. 2015. PMID: 25909291 Free PMC article.

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