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Tyrosinase-Mediated Synthesis of Nanobody-Cell Conjugates.
Maza JC, García-Almedina DM, Boike LE, Hamlish NX, Nomura DK, Francis MB. Maza JC, et al. Among authors: nomura dk. ACS Cent Sci. 2022 Jul 27;8(7):955-962. doi: 10.1021/acscentsci.1c01265. Epub 2022 Jun 22. ACS Cent Sci. 2022. PMID: 35912347 Free PMC article.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, Frank AO, Fuller D, Estes AR, Randal KL, Panidapu A, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Henning NJ, et al. Among authors: nomura dk. Nat Chem Biol. 2022 Apr;18(4):412-421. doi: 10.1038/s41589-022-00971-2. Epub 2022 Feb 24. Nat Chem Biol. 2022. PMID: 35210618 Free PMC article.
Advances in covalent drug discovery.
Boike L, Henning NJ, Nomura DK. Boike L, et al. Among authors: nomura dk. Nat Rev Drug Discov. 2022 Dec;21(12):881-898. doi: 10.1038/s41573-022-00542-z. Epub 2022 Aug 25. Nat Rev Drug Discov. 2022. PMID: 36008483 Free PMC article. Review.
A covalent inhibitor targeting the papain-like protease from SARS-CoV-2 inhibits viral replication.
Han H, Gracia AV, Røise JJ, Boike L, Leon K, Schulze-Gahmen U, Stentzel MR, Bajaj T, Chen D, Li IC, He M, Behrouzi K, Khodabakhshi Z, Nomura DK, Mofrad MRK, Kumar GR, Ott M, Murthy N. Han H, et al. Among authors: nomura dk. RSC Adv. 2023 Apr 4;13(16):10636-10641. doi: 10.1039/d3ra00426k. eCollection 2023 Apr 3. RSC Adv. 2023. PMID: 37025664 Free PMC article.
Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors.
Moon P, Zammit CM, Shao Q, Dovala D, Boike L, Henning NJ, Knapp M, Spradlin JN, Ward CC, Wolleb H, Fuller D, Blake G, Murphy JP, Wang F, Lu Y, Moquin SA, Tandeske L, Hesse MJ, McKenna JM, Tallarico JA, Schirle M, Toste FD, Nomura DK. Moon P, et al. Among authors: nomura dk. Chembiochem. 2023 Jun 1;24(11):e202300116. doi: 10.1002/cbic.202300116. Epub 2023 May 3. Chembiochem. 2023. PMID: 37069799
Rational Chemical Design of Molecular Glue Degraders.
Toriki ES, Papatzimas JW, Nishikawa K, Dovala D, Frank AO, Hesse MJ, Dankova D, Song JG, Bruce-Smythe M, Struble H, Garcia FJ, Brittain SM, Kile AC, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Toriki ES, et al. Among authors: nomura dk. ACS Cent Sci. 2023 Apr 11;9(5):915-926. doi: 10.1021/acscentsci.2c01317. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252349 Free PMC article.
DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders.
Lim M, Cong TD, Orr LM, Toriki ES, Kile AC, Papatzimas JW, Lee E, Lin Y, Nomura DK. Lim M, et al. Among authors: nomura dk. ACS Cent Sci. 2024 May 17;10(7):1318-1331. doi: 10.1021/acscentsci.4c00286. eCollection 2024 Jul 24. ACS Cent Sci. 2024. PMID: 39071058 Free PMC article.
183 results