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A highly efficacious live attenuated mumps virus-based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike.
Zhang Y, Lu M, Mahesh KC, Kim E, Shamseldin MM, Ye C, Dravid P, Chamblee M, Park JG, Hall JM, Trivedi S, Chaiwatpongsakorn S, Kenny AD, Murthy SS, Sharma H, Liang X, Yount JS, Kapoor A, Martinez-Sobrido L, Dubey P, Boyaka PN, Peeples ME, Li J. Zhang Y, et al. Among authors: murthy ss. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2201616119. doi: 10.1073/pnas.2201616119. Epub 2022 Jul 27. Proc Natl Acad Sci U S A. 2022. PMID: 35895717 Free PMC article.
Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model.
Trivedi S, Murthy S, Sharma H, Hartlage AS, Kumar A, Gadi SV, Simmonds P, Chauhan LV, Scheel TKH, Billerbeck E, Burbelo PD, Rice CM, Lipkin WI, Vandegrift K, Cullen JM, Kapoor A. Trivedi S, et al. Hepatology. 2018 Aug;68(2):435-448. doi: 10.1002/hep.29494. Epub 2018 May 21. Hepatology. 2018. PMID: 28859226 Free PMC article.
SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern.
Lu M, Chamblee M, Zhang Y, Ye C, Dravid P, Park JG, Mahesh KC, Trivedi S, Murthy S, Sharma H, Cassady C, Chaiwatpongsakorn S, Liang X, Yount JS, Boyaka PN, Peeples ME, Martinez-Sobrido L, Kapoor A, Li J. Lu M, et al. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2110105119. doi: 10.1073/pnas.2110105119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994646 Free PMC article.
Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse.
Nennig K, Murthy S, Maloney S, Shaw TM, Sharobim M, Matkovic E, Fadiran S, Larsen M, Ramuta MD, Kim AS, Teijaro JR, Grove J, Stremlau M, Sharma H, Trivedi S, Blum MJ, O'Connor DH, Hyde JL, Stapleton JT, Kapoor A, Bailey AL. Nennig K, et al. PLoS Pathog. 2024 Aug 28;20(8):e1012436. doi: 10.1371/journal.ppat.1012436. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39196893 Free PMC article.
Presence of Segmented Flavivirus Infections in North America.
Vandegrift KJ, Kumar A, Sharma H, Murthy S, Kramer LD, Ostfeld S, Hudson PJ, Kapoor A. Vandegrift KJ, et al. Emerg Infect Dis. 2020 Aug;26(8):1810-1817. doi: 10.3201/eid2608.190986. Emerg Infect Dis. 2020. PMID: 32687041 Free PMC article.
111 results