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The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.
Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB, Chang D, Bailey P, Scarpa A, Lawlor R, Chelala C, Keyse SM, Biankin A, Morton JP, Evans TJ, Barry ST, Sansom OJ, Kocher HM, Marshall JF. Reader CS, et al. Among authors: marshall jf. J Pathol. 2019 Nov;249(3):332-342. doi: 10.1002/path.5320. Epub 2019 Jul 30. J Pathol. 2019. PMID: 31259422 Free PMC article.
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion.
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall JJT, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler EJ, Singh N, Reader CS, Carter EP, Hodivala-Dilke K, Grose RP, Kocher HM, Gavara N, Pearce O, Cutillas P, Marshall JF, Cameron AJM. Murray ER, et al. Among authors: marshall jjt, marshall jf. Cell Rep. 2022 Jan 25;38(4):110227. doi: 10.1016/j.celrep.2021.110227. Cell Rep. 2022. PMID: 35081338 Free PMC article.
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.
Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T, Marshall JF, Kocher HM, Crnogorac-Jurcevic T, Scarpa A, Lemoine NR, Chelala C. Haider S, et al. Among authors: marshall jf. Genome Med. 2014 Dec 3;6(12):105. doi: 10.1186/s13073-014-0105-3. eCollection 2014. Genome Med. 2014. PMID: 25587357 Free PMC article.
Generation and characterization of a diabody targeting the αvβ6 integrin.
Kogelberg H, Miranda E, Burnet J, Ellison D, Tolner B, Foster J, Picón C, Thomas GJ, Meyer T, Marshall JF, Mather SJ, Chester K. Kogelberg H, et al. Among authors: marshall jf. PLoS One. 2013 Sep 4;8(9):e73260. doi: 10.1371/journal.pone.0073260. eCollection 2013. PLoS One. 2013. PMID: 24023846 Free PMC article.
Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.
Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A, Costa-Guerra JA, Violette S, Itamochi H, Ghaem-Maghami S, Vallath S, Marshall JF, Maher J. Whilding LM, et al. Among authors: marshall jf. Mol Ther. 2017 Jan 4;25(1):259-273. doi: 10.1016/j.ymthe.2016.10.012. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129120 Free PMC article.
338 results