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Gene regulatory control of myocardial energy metabolism predicts postoperative cardiac function in patients undergoing off-pump coronary artery bypass graft surgery: inhalational versus intravenous anesthetics.
Lucchinetti E, Hofer C, Bestmann L, Hersberger M, Feng J, Zhu M, Furrer L, Schaub MC, Tavakoli R, Genoni M, Zollinger A, Zaugg M. Lucchinetti E, et al. Among authors: zaugg m. Anesthesiology. 2007 Mar;106(3):444-57. doi: 10.1097/00000542-200703000-00008. Anesthesiology. 2007. PMID: 17325502 Clinical Trial.
Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift.
Wang L, Ko KW, Lucchinetti E, Zhang L, Troxler H, Hersberger M, Omar MA, Posse de Chaves EI, Lopaschuk GD, Clanachan AS, Zaugg M. Wang L, et al. Among authors: zaugg m. Anesthesiology. 2010 Sep;113(3):541-51. doi: 10.1097/ALN.0b013e3181e2c1a1. Anesthesiology. 2010. PMID: 20683255
The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.
Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M. Lou PH, et al. Among authors: zaugg m. PLoS One. 2014 Jan 30;9(1):e87205. doi: 10.1371/journal.pone.0087205. eCollection 2014. PLoS One. 2014. PMID: 24498043 Free PMC article.
122 results