Ewert S - Search Results

1

Computational counterselection identifies nonspecific therapeutic biologic candidates.

Saksena SD, Liu G, Banholzer C, Horny G, Ewert S, Gifford DK. Saksena SD, et al. Among authors: ewert s. Cell Rep Methods. 2022 Jul 11;2(7):100254. doi: 10.1016/j.crmeth.2022.100254. eCollection 2022 Jul 18. Cell Rep Methods. 2022. PMID: 35880012 Free PMC article.

2

Antibody complementarity determining region design using high-capacity machine learning.

Liu G, Zeng H, Mueller J, Carter B, Wang Z, Schilz J, Horny G, Birnbaum ME, Ewert S, Gifford DK. Liu G, et al. Among authors: ewert s. Bioinformatics. 2020 Apr 1;36(7):2126-2133. doi: 10.1093/bioinformatics/btz895. Bioinformatics. 2020. PMID: 31778140 Free PMC article.

3

Ultra-high-diversity factorizable libraries for efficient therapeutic discovery.

Dai Z, Saksena SD, Horny G, Banholzer C, Ewert S, Gifford DK. Dai Z, et al. Among authors: ewert s. Genome Res. 2022 Sep 27;32(9):1787-1794. doi: 10.1101/gr.276593.122. Genome Res. 2022. PMID: 35738900 Free PMC article.

4

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.

Koch AW, Schiering N, Melkko S, Ewert S, Salter J, Zhang Y, McCormack P, Yu J, Huang X, Chiu YH, Chen Z, Schleeger S, Horny G, DiPetrillo K, Muller L, Hein A, Villard F, Scharenberg M, Ramage P, Hassiepen U, Côté S, DeGagne J, Krantz C, Eder J, Stoll B, Kulmatycki K, Feldman DL, Hoffmann P, Basson CT, Frost RJA, Khder Y. Koch AW, et al. Among authors: ewert s. Blood. 2019 Mar 28;133(13):1507-1516. doi: 10.1182/blood-2018-10-880849. Epub 2019 Jan 28. Blood. 2019. PMID: 30692123 Free article.

5

Protective anti-prion antibodies in human immunoglobulin repertoires.

Senatore A, Frontzek K, Emmenegger M, Chincisan A, Losa M, Reimann R, Horny G, Guo J, Fels S, Sorce S, Zhu C, George N, Ewert S, Pietzonka T, Hornemann S, Aguzzi A. Senatore A, et al. Among authors: ewert s. EMBO Mol Med. 2020 Sep 7;12(9):e12739. doi: 10.15252/emmm.202012739. Epub 2020 Aug 10. EMBO Mol Med. 2020. PMID: 32776637 Free PMC article.

6

Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies.

Lu H, Molony RD, Chen D, Jang S, Wolf B, Ewert S, Flaherty M, Xu F, Isim S, Shim Y, Dornelas C, Balke N, Leber XC, Scharenberg M, Koelln J, Choi E, Ward R, Johnson J, Calzascia T, Isnardi I, Williams JA, Lindenbergh PL, van de Donk NWCJ, Mutis T, Huet H, Lees E, Meyer MJ. Lu H, et al. Among authors: ewert s. Mol Cancer Ther. 2020 Oct;19(10):2089-2104. doi: 10.1158/1535-7163.MCT-19-0003. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847974

7

Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry.

Hagman C, Ricke D, Ewert S, Bek S, Falchetto R, Bitsch F. Hagman C, et al. Among authors: ewert s. Anal Chem. 2008 Feb 15;80(4):1290-6. doi: 10.1021/ac702115b. Epub 2008 Jan 25. Anal Chem. 2008. PMID: 18217771

8

Reconstruction of full antibody sequences in NGS datasets and accurate V_L:V_H coupling by cluster coordinate matching of non-overlapping reads.

Moura-Sampaio J, Faustino AF, Boeuf R, Antunes MA, Ewert S, Batista AP. Moura-Sampaio J, et al. Among authors: ewert s. Comput Struct Biotechnol J. 2022 May 31;20:2723-2727. doi: 10.1016/j.csbj.2022.05.054. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35832623 Free PMC article.

9

Biophysical properties of human antibody variable domains.

Ewert S, Huber T, Honegger A, Plückthun A. Ewert S, et al. J Mol Biol. 2003 Jan 17;325(3):531-53. doi: 10.1016/s0022-2836(02)01237-8. J Mol Biol. 2003. PMID: 12498801

10

Biophysical properties of camelid V(HH) domains compared to those of human V(H)3 domains.

Ewert S, Cambillau C, Conrath K, Plückthun A. Ewert S, et al. Biochemistry. 2002 Mar 19;41(11):3628-36. doi: 10.1021/bi011239a. Biochemistry. 2002. PMID: 11888279

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