Ouyang L - Search Results

1

Polo-like Kinase 1 Inhibitors in Human Cancer Therapy: Development and Therapeutic Potential.

Zhang J, Zhang L, Wang J, Ouyang L, Wang Y. Zhang J, et al. Among authors: ouyang l. J Med Chem. 2022 Aug 11;65(15):10133-10160. doi: 10.1021/acs.jmedchem.2c00614. Epub 2022 Jul 25. J Med Chem. 2022. PMID: 35878418 Review.

2

Selective bone targeting 5-fluorouracil prodrugs: synthesis and preliminary biological evaluation.

Ouyang L, He D, Zhang J, He G, Jiang B, Wang Q, Chen Z, Pan J, Li Y, Guo L. Ouyang L, et al. Bioorg Med Chem. 2011 Jun 15;19(12):3750-6. doi: 10.1016/j.bmc.2011.05.004. Epub 2011 May 8. Bioorg Med Chem. 2011. PMID: 21612935

3

Untangling knots between autophagic targets and candidate drugs, in cancer therapy.

Xie T, Li SJ, Guo MR, Wu Y, Wang HY, Zhang K, Zhang X, Ouyang L, Liu J. Xie T, et al. Among authors: ouyang l. Cell Prolif. 2015 Apr;48(2):119-39. doi: 10.1111/cpr.12167. Epub 2015 Feb 4. Cell Prolif. 2015. PMID: 25650136 Free PMC article. Review.

4

Design and synthesis of a novel candidate compound NTI-007 targeting sodium taurocholate cotransporting polypeptide [NTCP]-APOA1-HBx-Beclin1-mediated autophagic pathway in HBV therapy.

Zhang J, Fu LL, Tian M, Liu HQ, Li JJ, Li Y, He J, Huang J, Ouyang L, Gao HY, Wang JH. Zhang J, et al. Among authors: ouyang l. Bioorg Med Chem. 2015 Mar 1;23(5):976-84. doi: 10.1016/j.bmc.2015.01.020. Epub 2015 Jan 19. Bioorg Med Chem. 2015. PMID: 25650312

5

Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery.

Fu LL, Tian M, Li X, Li JJ, Huang J, Ouyang L, Zhang Y, Liu B. Fu LL, et al. Among authors: ouyang l. Oncotarget. 2015 Mar 20;6(8):5501-16. doi: 10.18632/oncotarget.3551. Oncotarget. 2015. PMID: 25849938 Free PMC article. Review.

6

Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.

Zhang J, Jiang X, Jiang Y, Guo M, Zhang S, Li J, He J, Liu J, Wang J, Ouyang L. Zhang J, et al. Among authors: ouyang l. Eur J Med Chem. 2016 Jan 27;108:495-504. doi: 10.1016/j.ejmech.2015.12.016. Epub 2015 Dec 13. Eur J Med Chem. 2016. PMID: 26717201 Review.

7

Emerging targets and new small molecule therapies in Parkinson's disease treatment.

Zhang H, Tong R, Bai L, Shi J, Ouyang L. Zhang H, et al. Among authors: ouyang l. Bioorg Med Chem. 2016 Apr 1;24(7):1419-30. doi: 10.1016/j.bmc.2016.02.030. Epub 2016 Feb 24. Bioorg Med Chem. 2016. PMID: 26935940 Review.

8

Development of 4,5-dihydro-benzodiazepinone derivatives as a new chemical series of BRD4 inhibitors.

Li J, Wang P, Zhou B, Shi J, Liu J, Li X, Fan L, Zheng Y, Ouyang L. Li J, et al. Among authors: ouyang l. Eur J Med Chem. 2016 Oct 4;121:294-299. doi: 10.1016/j.ejmech.2016.05.057. Epub 2016 May 27. Eur J Med Chem. 2016. PMID: 27266999

9

What structural modifications can be used for BRD4 inhibitors for their use in leukemia therapy?

Yao D, Liu J, Ouyang L. Yao D, et al. Among authors: ouyang l. Future Med Chem. 2017 Jun;9(9):839-842. doi: 10.4155/fmc-2017-0084. Epub 2017 Jun 21. Future Med Chem. 2017. PMID: 28635318 No abstract available.

10

Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer.

Yao D, Zhou Y, Zhu L, Ouyang L, Zhang J, Jiang Y, Zhao Y, Sun D, Yang S, Yu Y, Wang J. Yao D, et al. Among authors: ouyang l. Eur J Med Chem. 2017 Nov 10;140:155-171. doi: 10.1016/j.ejmech.2017.08.067. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28923383

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