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The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation.
Senatore E, Chiuso F, Rinaldi L, Intartaglia D, Delle Donne R, Pedone E, Catalanotti B, Pirone L, Fiorillo B, Moraca F, Giamundo G, Scala G, Raffeiner A, Torres-Quesada O, Stefan E, Kwiatkowski M, van Pijkeren A, Morleo M, Franco B, Garbi C, Conte I, Feliciello A. Senatore E, et al. Among authors: feliciello a. EMBO J. 2021 May 17;40(10):e106503. doi: 10.15252/embj.2020106503. Epub 2021 May 2. EMBO J. 2021. PMID: 33934390 Free PMC article.
Pathophysiology of Primary Cilia: Signaling and Proteostasis Regulation.
Senatore E, Iannucci R, Chiuso F, Delle Donne R, Rinaldi L, Feliciello A. Senatore E, et al. Among authors: feliciello a. Front Cell Dev Biol. 2022 May 11;10:833086. doi: 10.3389/fcell.2022.833086. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35646931 Free PMC article. Review.
Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth.
Delle Donne R, Iannucci R, Rinaldi L, Roberto L, Oliva MA, Senatore E, Borzacchiello D, Lignitto L, Giurato G, Rizzo F, Sellitto A, Chiuso F, Castaldo S, Scala G, Campani V, Nele V, De Rosa G, D'Ambrosio C, Garbi C, Scaloni A, Weisz A, Ambrosino C, Arcella A, Feliciello A. Delle Donne R, et al. Among authors: feliciello a. Commun Biol. 2022 Aug 2;5(1):780. doi: 10.1038/s42003-022-03639-8. Commun Biol. 2022. PMID: 35918402 Free PMC article.
Ubiquitylation of BBSome is required for ciliary assembly and signaling.
Chiuso F, Delle Donne R, Giamundo G, Rinaldi L, Borzacchiello D, Moraca F, Intartaglia D, Iannucci R, Senatore E, Lignitto L, Garbi C, Conflitti P, Catalanotti B, Conte I, Feliciello A. Chiuso F, et al. Among authors: feliciello a. EMBO Rep. 2023 Apr 5;24(4):e55571. doi: 10.15252/embr.202255571. Epub 2023 Feb 6. EMBO Rep. 2023. PMID: 36744302 Free PMC article.
Downregulation of praja2 restrains endocytosis and boosts tyrosine kinase receptors in kidney cancer.
Rinaldi L, Chiuso F, Senatore E, Borzacchiello D, Lignitto L, Iannucci R, Donne RD, Fuggi M, Reale C, Russo F, Russo NA, Giurato G, Rizzo F, Sellitto A, Santangelo M, De Biase D, Paciello O, D'Ambrosio C, Amente S, Garbi C, Dalla E, Scaloni A, Weisz A, Ambrosino C, Insabato L, Feliciello A. Rinaldi L, et al. Among authors: feliciello a. Commun Biol. 2024 Feb 20;7(1):208. doi: 10.1038/s42003-024-05823-4. Commun Biol. 2024. PMID: 38379085 Free PMC article.
Author Correction: Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth.
Delle Donne R, Iannucci R, Rinaldi L, Roberto L, Oliva MA, Senatore E, Borzacchiello D, Lignitto L, Giurato G, Rizzo F, Sellitto A, Chiuso F, Castaldo S, Scala G, Campani V, Nele V, De Rosa G, D'Ambrosio C, Garbi C, Scaloni A, Weisz A, Ambrosino C, Arcella A, Feliciello A. Delle Donne R, et al. Among authors: feliciello a. Commun Biol. 2024 Oct 29;7(1):1411. doi: 10.1038/s42003-024-07075-8. Commun Biol. 2024. PMID: 39472761 Free PMC article. No abstract available.
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.
Lignitto L, Arcella A, Sepe M, Rinaldi L, Delle Donne R, Gallo A, Stefan E, Bachmann VA, Oliva MA, Tiziana Storlazzi C, L'Abbate A, Brunetti A, Gargiulo S, Gramanzini M, Insabato L, Garbi C, Gottesman ME, Feliciello A. Lignitto L, et al. Among authors: feliciello a. Nat Commun. 2013;4:1822. doi: 10.1038/ncomms2791. Nat Commun. 2013. PMID: 23652010 Free PMC article.
152 results