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107 results

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Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration.
Ramírez-Pardo I, Villarejo-Zori B, Jiménez-Loygorri JI, Sierra-Filardi E, Alonso-Gil S, Mariño G, de la Villa P, Fitze PS, Fuentes JM, García-Escudero R, Ferrington DA, Gomez-Sintes R, Boya P. Ramírez-Pardo I, et al. Among authors: de la villa p. Autophagy. 2023 Mar;19(3):784-804. doi: 10.1080/15548627.2022.2103307. Epub 2022 Jul 24. Autophagy. 2023. PMID: 35875981 Free PMC article.
Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa.
Corrochano S, Barhoum R, Boya P, Arroba AI, Rodríguez-Muela N, Gómez-Vicente V, Bosch F, de Pablo F, de la Villa P, de la Rosa EJ. Corrochano S, et al. Among authors: de la rosa ej, de pablo f, de la villa p. Invest Ophthalmol Vis Sci. 2008 Sep;49(9):4188-94. doi: 10.1167/iovs.08-2182. Epub 2008 May 30. Invest Ophthalmol Vis Sci. 2008. PMID: 18515565 Free article.
Balance between autophagic pathways preserves retinal homeostasis.
Rodríguez-Muela N, Koga H, García-Ledo L, de la Villa P, de la Rosa EJ, Cuervo AM, Boya P. Rodríguez-Muela N, et al. Among authors: de la rosa ej, de la villa p. Aging Cell. 2013 Jun;12(3):478-88. doi: 10.1111/acel.12072. Epub 2013 Apr 19. Aging Cell. 2013. PMID: 23521856 Free PMC article.
Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.
Sánchez-Cruz A, Villarejo-Zori B, Marchena M, Zaldivar-Díez J, Palomo V, Gil C, Lizasoain I, de la Villa P, Martínez A, de la Rosa EJ, Hernández-Sánchez C. Sánchez-Cruz A, et al. Among authors: de la rosa ej, de la villa p. Mol Neurodegener. 2018 Apr 16;13(1):19. doi: 10.1186/s13024-018-0251-y. Mol Neurodegener. 2018. PMID: 29661219 Free PMC article.
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice.
Samardzija M, Corna A, Gomez-Sintes R, Jarboui MA, Armento A, Roger JE, Petridou E, Haq W, Paquet-Durand F, Zrenner E, de la Villa P, Zeck G, Grimm C, Boya P, Ueffing M, Trifunović D. Samardzija M, et al. Among authors: de la villa p. Cell Death Differ. 2021 Apr;28(4):1317-1332. doi: 10.1038/s41418-020-00653-3. Epub 2020 Nov 6. Cell Death Differ. 2021. PMID: 33159184 Free PMC article.
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
Gomez-Sintes R, Xin Q, Jimenez-Loygorri JI, McCabe M, Diaz A, Garner TP, Cotto-Rios XM, Wu Y, Dong S, Reynolds CA, Patel B, de la Villa P, Macian F, Boya P, Gavathiotis E, Cuervo AM. Gomez-Sintes R, et al. Among authors: de la villa p. Nat Commun. 2022 Jul 21;13(1):4220. doi: 10.1038/s41467-022-31869-1. Nat Commun. 2022. PMID: 35864098 Free PMC article.
SOX2 haploinsufficiency promotes impaired vision at advanced age.
Moreno-Cugnon L, Anasagasti A, Ezquerra-Inchausti M, Izeta A, de la Villa P, Ruiz-Ederra J, Matheu A. Moreno-Cugnon L, et al. Among authors: de la villa p. Oncotarget. 2018 Nov 30;9(94):36684-36692. doi: 10.18632/oncotarget.26393. eCollection 2018 Nov 30. Oncotarget. 2018. PMID: 30613351 Free PMC article.
Functional and structural modifications during retinal degeneration in the rd10 mouse.
Barhoum R, Martínez-Navarrete G, Corrochano S, Germain F, Fernandez-Sanchez L, de la Rosa EJ, de la Villa P, Cuenca N. Barhoum R, et al. Among authors: de la rosa ej, de la villa p. Neuroscience. 2008 Aug 26;155(3):698-713. doi: 10.1016/j.neuroscience.2008.06.042. Epub 2008 Jul 3. Neuroscience. 2008. PMID: 18639614
107 results